製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CACNB3
  • 特異性
    This antibody recognises the beta 3 calcium channel subunit.
  • アプリケーション
    適用あり: WB, IP, ICC/IFmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Synthetic peptide:

    MYDDSYVPGFEDSEA

    conjugated to KLH, corresponding to amino acids 1-15 of CACNB3.

  • ポジティブ・コントロール
    • Rat cortical and hippocampal, neuronal membranes. Negative control: non neuronal cells

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.08% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab16717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 58 kDa.
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

ターゲット情報

  • 機能
    The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • 組織特異性
    Expressed mostly in brain, smooth muscle and ovary.
  • 配列類似性
    Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CAB3 antibody
    • CACB3_HUMAN antibody
    • Cacnb3 antibody
    • CACNLB3 antibody
    • Calcium channel voltage dependent beta 3 subunit antibody
    • Calcium channel voltage-dependent subunit beta 3 antibody
    • FLJ58949 antibody
    • Voltage-dependent L-type calcium channel subunit beta-3 antibody
    see all

Anti-CACNB3 antibody 画像



  • Predicted band size : 58 kDa

    Image from Uriu Y et al, J Biol Chem. 2010 Jul 9;285(28):21750-67. Epub 2010 May 7, Fig 7. DOI 10.1074/jbc.M110.101311

Anti-CACNB3 antibody (ab16717) 使用論文

This product has been referenced in:
  • Uriu Y  et al. Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285:21750-67 (2010). WB ; Human . Read more (PubMed: 20452978) »

See 1 Publication for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Western blot
Sample
Rat Recombinant protein (recombinant protein from e.Coli)
Loading amount
10 µg
Specification
recombinant protein from e.Coli
Gel Running Conditions
Reduced Denaturing
Blocking step
Milk as blocking agent for 15 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
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投稿 Oct 23 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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