製品の概要

  • 製品名Anti-CACNA1I antibody
  • 製品の詳細
    Mouse monoclonal to CACNA1I
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: GLLRNRCFLE ENFTIQGDVA LPPYYQPEED DEMPFICSLS GDNGIMGCHE IPPLKEQGRE CCLSKDDVYD FGAGRQDLNA SGLCVNWNRY YNVCRTGSA, corresponding to amino acids 233-332 of Human CACNA1I

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab56439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Calcium channel CaV3.3 (a1I) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. In heart, they may be involved in pacemaker current. In neurons, too, these channels may play a secondary pacemaker role. Three genes encoding T-type Ca2+ channels have been cloned and designated as CaV3.1 (a1G), CaV3.2 (a1H) and CaV3.3 (a1I). While CaV3.1 (a 1G) and CaV3.2 (a1H) are widely expressed in various tissues, CaV3.3 (a1I) is primarily expressed in the central nervous system, where high expression was described in thalamic neurons. The Ca2+ current generated by the CaV3.3 channel displays much slower activation and inactivation compared to the currents produced by CaV3.1 and CaV3.2, suggesting it might play a different role in neuronal excitability.
    • 細胞内局在Membrane; multi-pass membrane protein.
    • 参照データベース
    • 別名
      • calcium channel, voltage-dependent, alpha 1I subunit antibody
      • cav 3.3 antibody
      • cav3.3 antibody
      • KIAA1120 antibody

    Anti-CACNA1I antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab56439 CACNA1I antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-CACNA1I antibody (ab56439) 使用論文

    ab56439 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab56439.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"