製品の概要

  • 製品名Anti-CABYR antibody
    CABYR 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CABYR
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 93-142 (SKVPTQMEKS TDTDEDNVTR TEYSDKTTQF PSVYAVPGTE QTEAVGGLSS) of Human CABYR (NP_722454).

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab122951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.
  • 組織特異性Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors.
  • 配列類似性Contains 1 RIIa domain.
  • 翻訳後修飾Isoform 1 is phosphorylated on tyrosine residues during in vitro capacitation. Isoform 3 and isoform 5 are phosphorylated by GSK3B in vitro. Dephosphorylation affects its ability to bind calcium.
  • 細胞内局在Cytoplasm > cytoskeleton. Cell projection > cilium > flagellum. Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella and Nucleus. Cytoplasm. Cell projection > cilium > flagellum. According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CABYR antibody
    • CABYR_HUMAN antibody
    • Calcium binding tyrosine-(Y)-phosphorylation regulated antibody
    • Calcium-binding protein 86 antibody
    • Calcium-binding tyrosine phosphorylation-regulated protein antibody
    • Cancer/testis antigen 88 antibody
    • CBP86 antibody
    • CT88 antibody
    • Fibrousheathin II antibody
    • Fibrousheathin-2 antibody
    • FSP-2 antibody
    • FSP2 antibody
    • Testis-specific calcium-binding protein CBP86 antibody
    see all

Anti-CABYR antibody 画像

  • Anti-CABYR antibody (ab122951) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 24 kDa

Anti-CABYR antibody (ab122951) 使用論文

ab122951 has not yet been referenced specifically in any publications.

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