製品の概要

  • 製品名Anti-C6 antibody [13H5]
    C6 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [13H5] to C6
  • アプリケーション適用あり: WB, IP, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    C6 protein purified from human plasma.

  • ポジティブ・コントロール
    • Human plasma

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.03% Sodium Azide
    Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride
  • Concentration information loading...
  • ポリ/モノモノクローナル
  • クローン名13H5
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab71942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution.
    IP: Use 2µl.
    WB: 1/2000. Detects a band of approximately 105 kDa (predicted molecular weight: 105 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
    • 関連疾患Defects in C6 are the cause of complement component 6 deficiency (C6D) [MIM:612446]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
    • 配列類似性Belongs to the complement C6/C7/C8/C9 family.
      Contains 1 EGF-like domain.
      Contains 2 Kazal-like domains.
      Contains 1 LDL-receptor class A domain.
      Contains 1 MACPF domain.
      Contains 2 Sushi (CCP/SCR) domains.
      Contains 3 TSP type-1 domains.
    • 翻訳後修飾All cysteine residues are assumed to be cross-linked to one another. Individual modules containing an even number of conserved cysteine residues are supposed to have disulfide linkages only within the same module.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AW111623 antibody
      • C6 antibody
      • CO6_HUMAN antibody
      • Complement component 6 antibody
      • Complement component C6 antibody
      see all

    Anti-C6 antibody [13H5] 画像

    • All lanes : Anti-C6 antibody [13H5] (ab71942) at 1/2000 dilution

      Lane 1 : C6 protein isolated from human plasma
      Lane 2 : Human plasma at 0.5 µl


      Predicted band size : 105 kDa
      Observed band size : 105 kDa

    Anti-C6 antibody [13H5] (ab71942) 使用論文

    This product has been referenced in:

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"