Anti-C5a-R 抗体 [10/92] (ab117579)
Key features and details
- Rat monoclonal [10/92] to C5a-R
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
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製品名
Anti-C5a-R antibody [10/92]
C5a-R 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [10/92] to C5a-R -
由来種
Rat -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse C5a-R. RBL-2H3 transfected cells
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ポジティブ・コントロール
- Mouse Kidney tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
10/92 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab117579の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 10 µg/ml.
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特記事項 |
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IHC-P
Use a concentration of 10 µg/ml. |
ターゲット情報
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機能
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
翻訳後修飾
Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 12273 Mouse
- SwissProt: P30993 Mouse
- SwissProt: Q3TZ86 Mouse
- Unigene: 247623 Mouse
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別名
- ANAPHYLATOXIN RECEPTOR antibody
- C5a anaphylatoxin chemotactic receptor antibody
- C5a anaphylatoxin receptor antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (4)
ab117579 は 4 報の論文で使用されています。
- Hu X et al. Respiratory Syncytial Virus Exacerbates Kidney Damages in IgA Nephropathy Mice via the C5a-C5aR1 Axis Orchestrating Th17 Cell Responses. Front Cell Infect Microbiol 9:151 (2019). PubMed: 31134161
- Song D et al. Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration. Mol Vis 23:210-218 (2017). IHC-Fr ; Mouse . PubMed: 28442885
- Hu X et al. Respiratory Syncytial Virus Exacerbates OVA-mediated asthma in mice through C5a-C5aR regulating CD4+T cells Immune Responses. Sci Rep 7:15207 (2017). IHC . PubMed: 29123203
- Li G et al. Neuroprotective effects of argatroban and C5a receptor antagonist (PMX53) following intracerebral haemorrhage. Clin Exp Immunol 175:285-95 (2014). PubMed: 24117111