製品の概要

  • 製品名Anti-C5 / C5b antibody
    C5 / C5b 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to C5 / C5b
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human C5/C5b.

    (Peptide available as ab46170.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in purified human C5 protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab46171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 mg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 188 kDa).

ターゲット情報

  • 関連性C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • C5 antibody
    • Complement C5 antibody
    • Complement component 5 antibody
    • CPAMD4 antibody

Anti-C5 / C5b antibody 画像

  • Anti-C5 / C5b antibody (ab46171) at 1 µg/ml + Human Complement C5 Protein at 0.1 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 188 kDa
    Observed band size : 74 kDa (why is the actual band size different from the predicted?)

Anti-C5 / C5b antibody (ab46171) 使用論文

ab46171 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab46171.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"