Anti-C5 / C5b 抗体 [568] (ab11879)

製品の概要

  • 製品名Anti-C5 / C5b antibody [568]
    C5 / C5b 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [568] to C5 / C5b
  • 特異性This antibody reacts with an epitope on C5 and on C5b.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Unfortunately, this information is considered to be commercially sensitive

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab11879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Use under non reducing condition. Predicted molecular weight: 188.3 kDa.

ターゲット情報

  • 関連性C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • C5 antibody
    • Complement C5 antibody
    • Complement component 5 antibody
    • CPAMD4 antibody

Anti-C5 / C5b antibody [568] (ab11879) 使用論文

ab11879 has not yet been referenced specifically in any publications.

Product Wall

ab11879 is only able to recognize whole C5 or C5b as the epitope lies in the C5b region. Therefore, there should not be any cross-reactivity with C5a.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"