製品の概要

  • 製品名Anti-C4BPA antibody
    C4BPA 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to C4BPA
  • アプリケーション適用あり: ICC/IF, IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponding to an internal region between amino acids 272-413 of the Human C4BPA protein (P04003).

  • ポジティブ・コントロール
    • Human blood vessel tissue. Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab121141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 1 - 4 µg/ml.
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Use buffer at pH 6 for antigen retrieval.
WB 1/250 - 1/500.

ターゲット情報

  • 機能Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
  • 組織特異性Chylomicrons in the plasma.
  • 配列類似性Contains 8 Sushi (CCP/SCR) domains.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C4b-binding protein alpha chain antibody
    • C4bp antibody
    • C4bpa antibody
    • C4BPA_HUMAN antibody
    • Complement component 4 binding protein alpha antibody
    • Complement component 4 binding protein antibody
    • Proline-rich protein antibody
    • PrP antibody
    • RP11-164O23.4 antibody
    see all

Anti-C4BPA antibody 画像

  • All lanes : Anti-C4BPA antibody (ab121141) at 1/250 dilution

    Lane 1 : Negative control (vector only transfected HEK293T lysate)
    Lane 2 : Over-expression Lysate [Co-expressed with a C-terminal proprietary tag (3.1 KDa)] in mammalian HEK293T cells
  • Immunohistochemical staining of Human blood vessel with ab121141 at 1/250 dilution, showing distinct positivity in blood plasma.

Anti-C4BPA antibody (ab121141) 使用論文

ab121141 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"