製品の概要

  • 製品名
  • 製品の詳細
    Chicken polyclonal to C4A
  • 特異性
    ab61965 gives only one precipitin arc in immunodiffusion against normal human serum or human C4. It reacts with alpha and beta chains in electroblotting.
  • アプリケーション
    適用あり: Immunodiffusion, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    full lenth native protein C4A (SwissProt P0C0L4) purified from human plasma.

  • ポジティブ・コントロール
    • Human serum.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.1% Sodium Azide
    Constituents: 0.9% Sodium chloride
  • Concentration information loading...
  • 精製度
    IgY fraction
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgY
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab61965 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Immunodiffusion Use a concentration of 1 - 3 mg/ml.
WB Use a concentration of 1 - 3 mg/ml. Predicted molecular weight: 35 kDa.

ターゲット情報

  • 関連性
    C4A is the acidic form of complement factor 4, part of the classical activation pathway. Human complement component C4 is polymorphic at two loci, C4A and C4B. The C4A alleles carry the Rodgers (Rg) while the C4B alleles carry the Chido (Ch) blood group antigens. C4 (either allele A or B) protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. During activation, the alpha chain is cleaved by C1 into C4a and C4b, and C4b stays linked to the beta and gamma chains. Further degradation of C4b by C1 into the inactive fragments C4c and C4d blocks the generation of C3 convertase.
  • 細胞内局在
    Secreted
  • 参照データベース
  • 別名
    • Acidic C4 antibody
    • Acidic complement C4 antibody
    • C3 and PZP like alpha 2 macroglobulin domain containing protein 2 antibody
    • C4 antibody
    • C4A anaphylatoxin antibody
    • C4A antibody
    • C4A2 antibody
    • C4A3 antibody
    • C4A4 antibody
    • C4A6 antibody
    • C4AD antibody
    • C4S antibody
    • CO4 antibody
    • Complement C4-A antibody
    • Complement component 4A antibody
    • Complement component 4A (Rodgers blood group) antibody
    • CPAMD2 antibody
    • RG antibody
    • Rodgers blood group antibody
    • Rodgers form of C4 antibody
    see all

プロトコール

参考文献

ab61965 has not yet been referenced specifically in any publications.

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