Anti-C4 binding protein 抗体 [10-07] (ab118876)

製品の概要

  • 製品名Anti-C4 binding protein antibody [10-07]
    C4 binding protein 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [10-07] to C4 binding protein
  • 特異性ab118876 recognizes complement C4 binding protein.
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native Human C4 binding protein (purified).

  • ポジティブ・コントロール
    • Human liver tissue
  • 特記事項


    There are three variants of C4 binding protein, composed of alpha and beta chains. The predominant form is a 570 kD complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kD homoheptamer of alpha chains or a 500 kD complex of 6 alpha chains and 1 beta chain. C4 binding protein is expressed in the blood serum.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 8.40
    Preservative: 0.1% Sodium azide
    Constituent: 99% Borate buffered saline
  • Concentration information loading...
  • 精製度Protein A purified
  • 一次抗体 備考There are three variants of C4 binding protein, composed of alpha and beta chains. The predominant form is a 570 kD complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kD homoheptamer of alpha chains or a 500 kD complex of 6 alpha chains and 1 beta chain. C4 binding protein is expressed in the blood serum.
  • ポリ/モノモノクローナル
  • クローン名10-07
  • アイソタイプIgG2b
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab118876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
  • 配列類似性Contains 3 Sushi (CCP/SCR) domains.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C4b binding protein beta chain antibody
    • C4b-binding protein beta chain antibody
    • C4BP antibody
    • C4BPB antibody
    • C4BPB_HUMAN antibody
    • Complement component 4 binding protein beta antibody
    • Complement component 4 binding protein beta chain antibody
    • Complement component 4-binding protein beta antibody
    • OTTHUMP00000034288 antibody
    • OTTHUMP00000034289 antibody
    • OTTHUMP00000034375 antibody
    • OTTHUMP0000003474 antibody
    • Proline rich protein antibody
    • PRP antibody
    see all

Anti-C4 binding protein antibody [10-07] 画像

  • ab118876, at 5 µg/ml, staining C4 binding protein in formalin fixed, paraffin embedded Human liver tissue by Immunohistochemistry.

Anti-C4 binding protein antibody [10-07] (ab118876) 使用論文

ab118876 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"