製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to C3IP1
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus
  • 免疫原

    Synthetic peptide corresponding to a region between amino acids 150-200 of Human C3IP1 (NP_067646.1).

  • ポジティブ・コントロール
    • HeLa whole cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab101994 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
  • 追加情報
    Is unsuitable for WB.
  • ターゲット情報

    • 機能
      Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
    • 組織特異性
      Highly expressed in testis and at lower levels in the submandibular salivary gland.
    • 配列類似性
      Contains 1 BTB (POZ) domain.
      Contains 6 Kelch repeats.
    • ドメイン
      The BTB domain is required for interaction with CUL3.
    • Information by UniProt
    • 参照データベース
    • 別名
      • C3IP1 antibody
      • CUL3 interacting protein 1 antibody
      • CUL3-interacting protein 1 antibody
      • DKIR antibody
      • DKIR homolog antibody
      • FLJ27152 antibody
      • hDKIR antibody
      • Kelch like 12 (Drosophila) antibody
      • Kelch like 12 antibody
      • Kelch like 12 variant antibody
      • Kelch like protein 12 antibody
      • Kelch like protein C3IP1 antibody
      • kelch-like family member 12 antibody
      • Kelch-like protein 12 antibody
      • KLH12_HUMAN antibody
      • KLHL 12 antibody
      • klhl12 antibody
      • OTTHUMP00000038799 antibody
      see all

    画像

    • ab101996 at 1 µg/ml staining C3IP1 in HeLa cell lysate immunoprecipitated using ab101994 at 3 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with an exposure time of 30 seconds

    プロトコール

    参考文献

    ab101994 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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