製品の概要

  • 製品名Anti-C2ORF25 antibody
    C2ORF25 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to C2ORF25
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 215-264 (RAEGYWADFI DPSSGLAFFG PYTNNTLFET DERYRHLGFS VDDLGCCKVI) of Human C2ORF25 (NP_056517)

  • ポジティブ・コントロール
    • human Fetal muscle lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab83554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay 1/62500.

WB Use a concentration of 1 µg/ml. Detects a band of approximately 39, 50 kDa (predicted molecular weight: 33 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Involved in cobalamin metabolism.
  • 組織特異性Widely expressed at high levels.
  • 関連疾患Defects in MMADHC are the cause of methylmalonic aciduria and homocystinuria type cblD (MMAHCD) [MIM:277410]. A disorder of cobalamin metabolism characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl). Clinical features include developmental delay, hyotonia, mental retardation, seizures, megaloblastic anemia. Some patients manifest combined methylmalonic aciduria and homocystinuria (referred to as cblD original), some have only isolated homocystinuria (cblD variant 1), and others have only methylmalonic aciduria (cblD variant 2).
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C2orf25 antibody
    • cblD antibody
    • Chromosome 2 open reading frame 25 antibody
    • CL25022 antibody
    • Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria antibody
    • Methylmalonic aciduria and homocystinuria type D protein antibody
    • methylmalonic aciduria and homocystinuria type D protein, mitochondrial antibody
    • mitochondrial antibody
    • MMAD_HUMAN antibody
    • Mmadhc antibody
    • Protein C2orf25, mitochondrial antibody
    see all

Anti-C2ORF25 antibody 画像

  • Anti-C2ORF25 antibody (ab83554) at 1 µg/ml + fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 33 kDa
    Observed band size : 39,50 kDa (why is the actual band size different from the predicted?)

Anti-C2ORF25 antibody (ab83554) 使用論文

ab83554 has not yet been referenced specifically in any publications.

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