製品の概要

  • 製品名Anti-C2 antibody
    C2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to C2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Hamster, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 150-180 of Human C2 (NP_000054).

  • ポジティブ・コントロール
    • CHO cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 83 kDa.

ターゲット情報

  • 機能Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor 4b to generate the C3 or C5 convertase.
  • 関連疾患Defects in C2 are the cause of complement component 2 deficiency (C2D) [MIM:217000]. A deficiency of the complement classical pathway associated with the development of autoimmune disorders, mainly systemic lupus erythematosus. Skin and joint manifestations are common and renal disease is relatively rare. Patients with complement component 2 deficiency are also reported to have recurrent or invasive infections.
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
    Contains 3 Sushi (CCP/SCR) domains.
    Contains 1 VWFA domain.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARMD14 antibody
    • C2 antibody
    • C3/C5 convertase antibody
    • CO2 antibody
    • CO2_HUMAN antibody
    • Complement C2 antibody
    • Complement C2a fragment antibody
    • complement component 2 antibody
    • DKFZp779M0311 antibody
    see all

Anti-C2 antibody 画像

  • Anti-C2 antibody (ab106978) at 1/500 dilution + CHO cell lysate at 35 µg

    Predicted band size : 83 kDa

Anti-C2 antibody (ab106978) 使用論文

ab106978 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106978.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"