製品の概要

  • 製品名Anti-C1s antibody
    C1s 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to C1s
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human C1s (NP_001725.1)

  • ポジティブ・コントロール
    • Human liver tissue lysate. C1s transfected 293T cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab89598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 77 kDa.

ターゲット情報

  • 機能C1s B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
  • 関連疾患Defects in C1S are the cause of complement component C1s deficiency (C1SD) [MIM:613783]. A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 2 CUB domains.
    Contains 1 EGF-like domain.
    Contains 1 peptidase S1 domain.
    Contains 2 Sushi (CCP/SCR) domains.
  • 翻訳後修飾The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Basic proline rich peptide IB 1 antibody
    • C1 esterase antibody
    • C1S antibody
    • C1S_HUMAN antibody
    • Complement C1s subcomponent antibody
    • Complement C1s subcomponent heavy chain antibody
    • Complement C1s subcomponent light chain antibody
    • Complement component 1 s subcomponent antibody
    • Complement component 1 subcomponent s antibody
    • FLJ44757 antibody
    see all

Anti-C1s antibody 画像

  • Anti-C1s antibody (ab89598) at 1 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 77 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-C1s antibody (ab89598) at 1 µg/ml

    Lane 1 : C1s transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 77 kDa
    Observed band size : 77 kDa

Anti-C1s antibody (ab89598) 使用論文

ab89598 has not yet been referenced specifically in any publications.

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Unfortunately we haven't tested this product for blocking the complement pathway proteins and we also haven't received any publication data which confirms its use in functional assays. I am sorry we are unable to c...

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