製品の概要

  • 製品名Anti-C1QC antibody
    C1QC 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to C1QC
  • 特異性detects endogenous levels of total C1QC protein.
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from internal sequence of Human C1QC (UniProt ID: P02747).

  • ポジティブ・コントロール
    • Rat lung cell lysate, Human lung carcinoma tissue

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
IHC-P
  • 追加情報ELISA: 1/40000.
    IHC-P: 1/50 - 1/100. Antigen retrieval is not essential but may optimise staining.
    WB: 1/500 - 1/1000. Predicted molecular weight: 26 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
    • 関連疾患Defects in C1QC are a cause of complement component C1q deficiency (C1QD) [MIM:613652]. A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
    • 配列類似性Contains 1 C1q domain.
      Contains 1 collagen-like domain.
    • 翻訳後修飾O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AI385742 antibody
      • C1Q C antibody
      • C1qc antibody
      • C1QC_HUMAN antibody
      • C1QG antibody
      • Complement C1q subcomponent subunit C antibody
      • Complement component 1, q subcomponent, C chain antibody
      • complement component 1, q subcomponent, gamma polypeptide antibody
      see all

    Anti-C1QC antibody 画像

    • All lanes : Anti-C1QC antibody (ab92689) at 1/500 dilution

      Lane 1 : Rat lung cell lysate in absence of blocking peptide
      Lane 2 : Rat lung cell lysate in presence of blocking peptide (10 µg)

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 26 kDa
    • ab92689 at 1/50 dilution staining C1QC in Human lung carcinoma in (1) absence of blocking peptide and (2) presence of blocking peptide by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

    Anti-C1QC antibody (ab92689) 使用論文

    ab92689 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92689.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"