製品の概要

  • 製品名Anti-C1q antibody (Biotin)
    C1q 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to C1q (Biotin)
  • 標識Biotin
  • アプリケーション適用あり: WB, RIAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human C1q purified from Human plasma.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab48341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 26 kDa.
RIA Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
  • 関連疾患Defects in C1QA are a cause of complement component C1q deficiency (C1QD) [MIM:613652]. A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis.
  • 配列類似性Contains 1 C1q domain.
    Contains 1 collagen-like domain.
  • 翻訳後修飾O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C1qa antibody
    • C1QA_HUMAN antibody
    • C1QB antibody
    • C1QC antibody
    • Complement C1q subcomponent subunit A antibody
    • Complement C1q subcomponent subunit B antibody
    • Complement C1q subcomponent subunit C antibody
    • Complement component 1 q subcomponent alpha polypeptide antibody
    • Complement component C1q A chain antibody
    • Complement component C1q B chain antibody
    • Complement component C1q C chain antibody
    see all

Anti-C1q antibody (Biotin) (ab48341) 使用論文

ab48341 has not yet been referenced specifically in any publications.

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