Anti-Draxin 抗体 (ab119707)
Key features and details
- Rabbit polyclonal to Draxin
- Suitable for: WB, ICC
- Reacts with: Mouse, Rat, Chicken
- Isotype: IgG
製品の概要
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製品名
Anti-Draxin antibody
Draxin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Draxin -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICCmore details -
種交差性
交差種: Mouse, Rat, Chicken
交差が予測される動物種: Human -
免疫原
Synthetic peptide corresponding to Human Draxin (C terminal) conjugated to keyhole limpet haemocyanin.
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ポジティブ・コントロール
- Rat PC12 cells and cell lysate; Rat P1 brain, chick E9 brain and adult Mouse brain lysates.
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特記事項
Do not aliquot.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab119707 was peptide affinity purified. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab119707の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 38 kDa).
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ICC |
1/100.
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特記事項 |
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WB
1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 38 kDa). |
ICC
1/100. |
ターゲット情報
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機能
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. -
配列類似性
Belongs to the draxin family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 419492 Chicken
- Entrez Gene: 374946 Human
- Entrez Gene: 70433 Mouse
- Entrez Gene: 691317 Rat
- Omim: 612682 Human
- SwissProt: Q8NBI3 Human
- SwissProt: Q6PAL1 Mouse
- Unigene: 632364 Human
see all -
別名
- AGPA3119 antibody
- Chromosome 1 open reading frame 187 antibody
- Dorsal inhibitory axon guidance protein antibody
see all
画像
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All lanes : Anti-Draxin antibody (ab119707) at 1/1000 dilution
Lane 1 : Rat PC12 cell lysate
Lane 2 : Rat P1 brain lysate
Lane 3 : Adult mouse brain lysate
Lane 4 : Chick E9 brain lysate
Predicted band size: 38 kDa -
ab119707 at 1/100 dilution staining Draxin in Rat PC12 cells, differentiated with NGF, by Immunocytochemistry in the absence (left) or presence (right) of blocking peptide. The lower images show corresponding phase images.
detection used an appropriate secondary antibody conjugated to Cy3.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab119707 は論文での使用が確認できていません。