製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to C1orf187
  • 由来種
    Rabbit
  • 特異性
    At least three isoforms of C1orf187 are known to exist; ab117452 will detect the two shorter isoforms. ab117452 is predicted to not cross-react with RILP.
  • アプリケーション
    適用あり: ICC/IF, WB, IHC-P, ICCmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide corresponding to 17 amino acids from the C terminal of Human C1orf187 (BAG80561).

  • ポジティブ・コントロール
    • Rat cerebellum tissue lysate.
  • 特記事項
    Avoid repeated freeze thaw cycles and exposure to prolonged high temperatures.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab117452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
IHC-P Use at an assay dependent concentration.
ICC Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能
    Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
  • 配列類似性
    Belongs to the draxin family.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AGPA3119 antibody
    • Chromosome 1 open reading frame 187 antibody
    • Dorsal inhibitory axon guidance protein antibody
    • Dorsal repulsive axon guidance protein antibody
    • DRAXI_HUMAN antibody
    • Draxin antibody
    • FLJ34999 antibody
    • MGC117222 antibody
    • Neucrin antibody
    • OTTHUMP00000002262 antibody
    • UNQ3119 antibody
    see all

画像

  • Immunofluorescence of C1orf187 in mouse brain tissue with ab117452 at 20 ug/mL.
  • Anti-C1orf187 antibody (ab117452) at 1 µg/ml + Rat cerebellum tissue lysate at 15 µg

    Predicted band size: 38 kDa

  • Immunohistochemical analysis of mouse brain tissue, staining C1orf187 with ab117452 at 5 µg/ml.

参考文献

ab117452 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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