製品の概要

  • 製品名Anti-C1orf149 antibody
  • 製品の詳細
    Rabbit polyclonal to C1orf149
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Synthetic peptide (Human)

  • ポジティブ・コントロール
    • Jurkat cell lysate; human kidney tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab42472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1:312500.

WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 22 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

ターゲット情報

  • 機能Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
  • 関連疾患A chromosomal aberration involving MEAF6 may be a cause of endometrial stromal tumors. Translocation t(1;6)(p34;p21) with PHF1.
  • 配列類似性Belongs to the EAF6 family.
  • 細胞内局在Nucleus, nucleolus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CDABP0189 antibody
    • Chromatin modification-related protein MEAF6 antibody
    • Chromosome 1 open reading frame 149 antibody
    • Eaf6 antibody
    • EAF6_HUMAN antibody
    • Esa1-associated factor 6 homolog antibody
    • FLJ11730 antibody
    • hEAF6 antibody
    • Hypothetical protein LOC64769 antibody
    • MEAF6 antibody
    • MYST/Esa1-associated factor 6 antibody
    • NY SAR 91 antibody
    • Protein EAF6 homolog antibody
    • RP3 423B22.2 antibody
    • Sarcoma antigen NY SAR 91 antibody
    • Sarcoma antigen NY-SAR-91 antibody
    see all

Anti-C1orf149 antibody 画像

  • Anti-C1orf149 antibody (ab42472) at 0.5 µg/ml + Jurkat cell lyste at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 22 kDa
    Observed band size : 24 kDa (why is the actual band size different from the predicted?)
  • ab42472 at 8µg/ml staining human kidney for C1orf149. Arrows indicate staining of epithelial cells of collecting tubules.

Anti-C1orf149 antibody (ab42472) 使用論文

ab42472 has not yet been referenced specifically in any publications.

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