製品の概要

  • 製品名Anti-C1GALT1C1 antibody - N-terminal
    C1GALT1C1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to C1GALT1C1 - N-terminal
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide selected from the N terminal region of Human C1GALT1C1 conjugated to KLH (NP_689905.1).

  • ポジティブ・コントロール
    • HeLa cell line lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab93483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 36 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1).
    • 組織特異性Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus.
    • 関連疾患Defects in C1GALT1C1 are the cause of Tn syndrome (TNSYN) [MIM:300622]. Tn syndrome is a rare autoimmune disease caused by somatic mutation in the C1GALT1C1 gene in which subpopulations of blood cells of all lineages carry an incompletely glycosylated membrane glycoprotein, i.e. the Tn antigen. Since leukocytes and platelets are affected as well as red cells, anemia, leukopenia and thrombocytopenia are features. Tn-polyagglutinability is sometimes associated with leukemia or is a preleukemic state.
    • 配列類似性Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • HSPC067 antibody
      • 3-galactosyltransferase 2 antibody
      • Beta 1,3 galactosyltransferase 2 antibody
      • Beta1,3 galactosyltransferase 2 antibody
      • C1Gal T2 antibody
      • C1Gal-T2 antibody
      • C1GALT1 specific chaperone 1 antibody
      • C1GALT1-specific chaperone 1 antibody
      • C1galt1c1 antibody
      • C1GalT2 antibody
      • C1GLC_HUMAN antibody
      • C38H2 L1 antibody
      • C38H2 like protein 1 antibody
      • C38H2-L1 antibody
      • C38H2-like protein 1 antibody
      • C38H2L1 antibody
      • Core 1 beta1 antibody
      • Core 1 beta3 galactosyltransferase specific molecular chaperone antibody
      • Core 1 beta3-Gal-T2 antibody
      • Core 1 beta3-galactosyltransferase-specific molecular chaperone antibody
      • Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1,3 galactosyltransferase 2 antibody
      • COSMC antibody
      • MGC19947 antibody
      • MST143 antibody
      see all

    Anti-C1GALT1C1 antibody - N-terminal 画像

    • Anti-C1GALT1C1 antibody - N-terminal (ab93483) at 1/100 dilution + HeLa cell line lysates at 35 µg

      Predicted band size : 36 kDa

    Anti-C1GALT1C1 antibody - N-terminal (ab93483) 使用論文

    This product has been referenced in:

    See 1 Publication for this product

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