製品の概要

  • 製品名Anti-C16orf57 antibody
    C16orf57 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to C16orf57
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-266 of Human C16orf57

  • ポジティブ・コントロール
    • transfected 293T cells lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab67059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 38 kDa (predicted molecular weight: 30 kDa).

ターゲット情報

  • 関連疾患Defects in C16orf57 are the cause of poikiloderma with neutropenia (PN) [MIM:604173]. PN is a genodermatosis characterized by poikiloderma, pachyonychia and chronic neutropenia. The disorder starts as a papular erythematous rash on the limbs during the first year of life. It gradually spreads centripetally and, as the papular rash resolves, hypo- and hyperpigmentation result, with development of telangiectasias. Another skin manifestation is pachyonychia, but alopecia and leukoplakia are distinctively absent. One of the most important extracutaneous symptoms is an increased susceptibility to infections, mainly affecting the respiratory system, primarily due to a chronic neutropenia and to neutrophil functional defects. Bone marrow abnormalities account for neutropenia and may evolve into myelodysplasia associated with the risk of leukemic transformation. Poikiloderma with neutropenia shows phenotypic overlap with Rothmund-Thomson syndrome.
  • 配列類似性Belongs to the UPF0406 family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C16orf57 antibody
    • Chromosome 16 open reading frame 57 antibody
    • CP057_HUMAN antibody
    • FLJ13154 antibody
    • UPF0406 protein C16orf57 antibody
    see all

Anti-C16orf57 antibody 画像

  • All lanes : Anti-C16orf57 antibody (ab67059) at 1/500 dilution

    Lane 1 : C16orf57 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 30 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)

Anti-C16orf57 antibody (ab67059) 使用論文

ab67059 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application Western blot
Sample Human Cell lysate - whole cell (WI-38)
Loading amount 50 µg
Specification WI-38
Gel Running Conditions Reduced Denaturing (12% gel)
Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
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投稿 Sep 16 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"