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RabMAb

Anti-c-Myc 抗体 [Y69] (ab32072)

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ab32072 は 191 報の論文で使用されています。

  • Weng S  et al. Restoration of MYC-repressed targets mediates the negative effects of GM-CSF on RUNX1-ETO leukemogenicity. Leukemia 31:159-169 (2017). WB . PubMed: 27389055
  • Lu T  et al. Adamts18 deficiency promotes colon carcinogenesis by enhancing ß-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer. Oncotarget 8:18979-18990 (2017). WB, IHC ; Mouse . PubMed: 28145888
  • Yuan H  et al. HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes. Sci Rep 7:45617 (2017). IHC-P ; Human . PubMed: 28378747
  • Barfeld SJ  et al. c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks. EBioMedicine 18:83-93 (2017). WB, IHC ; Human . PubMed: 28412251
  • Hogg SJ  et al. BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1. Cell Rep 18:2162-2174 (2017). ChIP ; Human . PubMed: 28249162
  • Ma L  et al. Long non-coding RNA XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer. Oncotarget 8:4125-4135 (2017). WB ; Human . PubMed: 27911852
  • Lines KE  et al. Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors. Oncogenesis 6:e332 (2017). WB ; Mouse . PubMed: 28504695
  • Xin B  et al. Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways. Oncogene N/A:N/A (2017). IHC-P ; Mouse . PubMed: 28481866
  • Malchenko S  et al. Stabilization of HIF-1a and HIF-2a, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model. PLoS One 12:e0173106 (2017). IHC-P ; Human . PubMed: 28249000
  • Baudin M  et al. Analysis of the ZAR1 Immune Complex Reveals Determinants for Immunity and Molecular Interactions. Plant Physiol 174:2038-2053 (2017). WB, IP ; Nicotiana benthamiana . PubMed: 28652264
  • Jiang XN  et al. Anaplastic lymphoma kinase-positive large B-cell lymphoma: Clinico-pathological study of 17 cases with review of literature. PLoS One 12:e0178416 (2017). IHC-P ; Human . PubMed: 28665943
  • Matkar S  et al. Kinase inhibitors of HER2/AKT pathway induce ERK phosphorylation via a FOXO-dependent feedback loop. Am J Cancer Res 7:1476-1485 (2017). WB ; Human . PubMed: 28744398
  • Yahiaoui A  et al. PI3Kd inhibitor idelalisib in combination with BTK inhibitor ONO/GS-4059 in diffuse large B cell lymphoma with acquired resistance to PI3Kd and BTK inhibitors. PLoS One 12:e0171221 (2017). WB, IHC . PubMed: 28178345
  • Marión RM  et al. Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis. Stem Cell Reports 8:460-475 (2017). PubMed: 28162998
  • Fan J  et al. A novel role of CKIP-1 in promoting megakaryocytic differentiation. Oncotarget 8:30138-30150 (2017). PubMed: 28404913
  • Heo MH  et al. IRF4/MUM1 expression is associated with poor survival outcomes in patients with peripheral T-cell lymphoma. J Cancer 8:1018-1024 (2017). PubMed: 28529614
  • Ishii N  et al. Poor prognosis in cholangiocarcinoma patients with low FBXW7 expression is improved by chemotherapy. Oncol Lett 13:3653-3661 (2017). PubMed: 28521468
  • Xiao J  et al. Efficacy and tolerability of chemotherapy in Chinese patients with AIDS-related Burkitt lymphoma and diffuse large B-cell lymphoma: An observational study. Sci Rep 7:1905 (2017). PubMed: 28507339
  • Tian C  et al. ABCG1 as a potential oncogene in lung cancer. Exp Ther Med 13:3189-3194 (2017). PubMed: 28588672
  • Bolognesi MM  et al. Multiplex Staining by Sequential Immunostaining and Antibody Removal on Routine Tissue Sections. J Histochem Cytochem 65:431-444 (2017). PubMed: 28692376
  • Wang S  et al. Fibulin-3 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition and activating the Wnt/ß-catenin signaling pathway. Sci Rep 7:6215 (2017). PubMed: 28740094
  • Peng Y  et al. Lovastatin Inhibits Cancer Stem Cells and Sensitizes to Chemo- and Photodynamic Therapy in Nasopharyngeal Carcinoma. J Cancer 8:1655-1664 (2017). PubMed: 28775785
  • Gupta N  et al. High Myc expression and transcription activity underlies intra-tumoral heterogeneity in triple-negative breast cancer. Oncotarget 8:28101-28115 (2017). IHC ; Human . PubMed: 28427212
  • Tang L  et al. Expression of NUAK2 in gastric cancer tissue and its effects on the proliferation of gastric cancer cells. Exp Ther Med 13:676-680 (2017). PubMed: 28352350
  • Wang JH  et al. Overexpression of MYC and BCL2 Predicts Poor Prognosis in Patients with Extranodal NK/T-cell Lymphoma, Nasal Type. J Cancer 8:793-800 (2017). PubMed: 28382141
  • Feng J  et al. Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells. Eur J Histochem 60:2711 (2016). PubMed: 28076932
  • Lee JY  et al. Novel Function of Sprouty4 as a Regulator of Stemness and Differentiation of Embryonic Stem Cells. Dev Reprod 20:171-7 (2016). WB . PubMed: 27660833
  • Tagde A  et al. MUC1-C drives MYC in multiple myeloma. Blood 127:2587-97 (2016). PubMed: 26907633
  • Tian-Zhong M  et al. Critical role of Emx2 in the pluripotency - differentiation transition in male gonocytes via regulation of FGF9/NODAL pathway. Reproduction 151:673-81 (2016). PubMed: 27002001
  • Feng D  et al. Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis. Oncotarget 7:64575-64588 (2016). WB ; Human . PubMed: 27602489
  • Kress TR  et al. Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors. Cancer Res 76:3463-72 (2016). PubMed: 27197165
  • Kang J  et al. Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription. Oncotarget 7:48887-48904 (2016). PubMed: 27385002
  • Li X  et al. SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer. Oncotarget 7:12869-84 (2016). IHC . PubMed: 26883200
  • Itkonen HM  et al. Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism. Oncotarget 7:12464-76 (2016). WB . PubMed: 26824323
  • Lynch JT  et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget 7:22128-39 (2016). PubMed: 26989080
  • Hellner K  et al. Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies. EBioMedicine 10:137-49 (2016). PubMed: 27492892
  • Yang CX  et al. MicroRNA-320 regulates the radiosensitivity of cervical cancer cells C33AR by targeting ß-catenin. Oncol Lett 12:4983-4990 (2016). WB . PubMed: 28105205
  • Camarda R  et al. Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med 22:427-32 (2016). WB . PubMed: 26950360
  • Liu T  et al. Capsaicin mediates caspases activation and induces apoptosis through P38 and JNK MAPK pathways in human renal carcinoma. BMC Cancer 16:790 (2016). PubMed: 27729033
  • Raina K  et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A 113:7124-9 (2016). PubMed: 27274052
  • Swetzig WM  et al. Estrogen receptor alpha (ERa/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer. Oncotarget 7:16049-69 (2016). WB . PubMed: 26909605
  • Shen H  et al. Lin28A activates androgen receptor via regulation of c-myc and promotes malignancy of ER-/Her2+ breast cancer. Oncotarget 7:60407-60418 (2016). WB . PubMed: 27494865
  • Hall Z  et al. Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer. Cancer Res 76:4608-18 (2016). IHC-P ; Human . PubMed: 27335109
  • Ma L  et al. Fat4 suppression induces Yap translocation accounting for the promoted proliferation and migration of gastric cancer cells. Cancer Biol Ther 17:36-47 (2016). WB ; Human . PubMed: 26575609
  • Wu Y  et al. Low expression of secreted frizzled-related protein 2 and nuclear accumulation of ß-catenin in aggressive nonfunctioning pituitary adenoma. Oncol Lett 12:199-206 (2016). WB ; Human . PubMed: 27347125
  • Li T  et al. Premalignant alteration assessment in liver-like tissue derived from embryonic stem cells by aristolochic acid I exposure. Oncotarget 7:78872-78882 (2016). ICC/IF ; Mouse . PubMed: 27713163
  • Nowacka JD  et al. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget 7:80113-80130 (2016). WB ; Human . PubMed: 27741509
  • Griffin NI  et al. ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC. Breast Cancer Res 18:113 (2016). WB ; Human . PubMed: 27852327
  • Yu Y  et al. Preterm infant gut microbiota affects intestinal epithelial development in a humanized microbiome gnotobiotic mouse model. Am J Physiol Gastrointest Liver Physiol 311:G521-32 (2016). IHC ; Human . PubMed: 27492329
  • Nakazawa MS  et al. Epigenetic re-expression of HIF-2a suppresses soft tissue sarcoma growth. Nat Commun 7:10539 (2016). WB . PubMed: 26837714
  • Hanaford AR  et al. DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets. Clin Cancer Res 22:3903-14 (2016). PubMed: 27012813
  • Oh EJ  et al. Long Non-coding RNA HOTAIR Expression in Diffuse Large B-Cell Lymphoma: In Relation to Polycomb Repressive Complex Pathway Proteins and H3K27 Trimethylation. J Pathol Transl Med 50:369-76 (2016). PubMed: 27550047
  • Sun X  et al. MAVS maintains mitochondrial homeostasis via autophagy. Cell Discov 2:16024 (2016). PubMed: 27551434
  • Maeshima AM  et al. Clinicopathological features of histological transformation from extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue to diffuse large B-cell lymphoma: an analysis of 467 patients. Br J Haematol 174:923-31 (2016). PubMed: 27460179
  • Huang YW  et al. Black raspberries demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell papilloma. Mol Carcinog 55:1867-1875 (2016). PubMed: 27696538
  • Choe JY  et al. PELI1 expression is correlated with MYC and BCL6 expression and associated with poor prognosis in diffuse large B-cell lymphoma. Mod Pathol 29:1313-1323 (2016). PubMed: 27469333
  • Gao K  et al. Deregulated WWOX is involved in a negative feedback loop with microRNA-214-3p in osteosarcoma. Int J Mol Med N/A:N/A (2016). WB . PubMed: 27840941
  • Courville EL  et al. EBV-negative monomorphic B-cell post-transplant lymphoproliferative disorders are pathologically distinct from EBV-positive cases and frequently contain TP53 mutations. Mod Pathol 29:1200-11 (2016). PubMed: 27443517
  • Gupta NK  et al. Long-term survival in AIDS-related primary central nervous system lymphoma. Neuro Oncol N/A:N/A (2016). PubMed: 27576871
  • Manerba M  et al. Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells. Eur J Pharm Sci 96:37-44 (2016). PubMed: 27622920
  • Rui L  et al. Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A 113:E7260-E7267 (2016). PubMed: 27799566
  • Dela Cruz FS  et al. A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma. Genome Med 8:116 (2016). WB . PubMed: 27799065
  • Wu C  et al. A positive feedback loop involving the Wnt/ß-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma. J Hematol Oncol 9:120 (2016). IHC, ICC/IF . PubMed: 27821172
  • Zhao X  et al. Inhibition of mTORC1 signaling sensitizes hepatocellular carcinoma cells to glycolytic stress. Am J Cancer Res 6:2289-2298 (2016). WB ; Human . PubMed: 27822418
  • Lorenzin F  et al. Different promoter affinities account for specificity in MYC-dependent gene regulation. Elife 5:N/A (2016). PubMed: 27460974
  • Shi X  et al. Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-ß-dependent mechanisms. Proc Natl Acad Sci U S A 113:E4558-66 (2016). PubMed: 27432991
  • Han A  et al. p63a modulates c-Myc activity via direct interaction and regulation of MM1 protein stability. Oncotarget 7:44277-44287 (2016). WB ; Human . PubMed: 27341130
  • Grampp S  et al. Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer. Nat Commun 7:13183 (2016). WB, IHC-P ; Human . PubMed: 27774982
  • Jin YJ  et al. Epidermal CYLD inactivation sensitizes mice to the development of sebaceous and basaloid skin tumors. JCI Insight 1:N/A (2016). IF, IHC . PubMed: 27478875
  • Lee KS  et al. Favorable prognosis in colorectal cancer patients with co-expression of c-MYC and ß-catenin. BMC Cancer 16:730 (2016). IHC-P ; Human . PubMed: 27619912
  • Qu F  et al. MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/ß-catenin pathway. Oncol Lett 11:1592-1596 (2016). WB ; Human . PubMed: 26893786
  • Park JW  et al. Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay. Proc Natl Acad Sci U S A 113:4482-7 (2016). PubMed: 27044116
  • Rennoll SA  et al. The MYC 3' Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells. Cancers (Basel) 8:N/A (2016). WB ; Human . PubMed: 27223305
  • Chung SI  et al. Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background. BMC Gastroenterol 16:13 (2016). WB, IHC-P . PubMed: 26821924
  • Boudjadi S  et al. Integrin a1ß1 expression is controlled by c-MYC in colorectal cancer cells. Oncogene 35:1671-8 (2016). WB, ChIP . PubMed: 26096932
  • Alexandrova S  et al. Selection and dynamics of embryonic stem cell integration into early mouse embryos. Development 143:24-34 (2016). PubMed: 26586221
  • Monaghan MG  et al. Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development. Development 143:473-82 (2016). PubMed: 26674310
  • Kluk MJ  et al. MYC Immunohistochemistry to Identify MYC-Driven B-Cell Lymphomas in Clinical Practice. Am J Clin Pathol 145:166-79 (2016). PubMed: 26834124
  • Franco M  et al. A Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells. MBio 7:e02231-15 (2016). WB . PubMed: 26838724
  • Agarwal R  et al. Role of immunohistochemistry in the era of genetic testing in MYC-positive aggressive B-cell lymphomas: a study of 209 cases. J Clin Pathol 69:266-70 (2016). PubMed: 26307073
  • Korangath P  et al. Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate. Clin Cancer Res 21:3263-73 (2015). WB ; Human . PubMed: 25813021
  • Bjorklund CC  et al. Rate of CRL4(CRBN) substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4. Blood Cancer J 5:e354 (2015). IHC ; Human . PubMed: 26430725
  • Chang BS  et al. Collagen complexes increase the efficiency of iPS cells generated using fibroblasts from adult mice. J Reprod Dev 61:145-53 (2015). IF ; Mouse . PubMed: 25740096
  • Meng QB  et al. Overexpression of eukaryotic translation initiation factor 5A2 (EIF5A2) correlates with cell aggressiveness and poor survival in gastric cancer. PLoS One 10:e0119229 (2015). PubMed: 25793713
  • Mamada H  et al. Cell competition in mouse NIH3T3 embryonic fibroblasts is controlled by the activity of Tead family proteins and Myc. J Cell Sci 128:790-803 (2015). WB, ICC/IF . PubMed: 25588835
  • Linley A  et al. Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells. Blood 126:1902-10 (2015). PubMed: 26194765
  • Ma L  et al. Trap Effect of Three-Dimensional Fibers Network for High Efficient Cancer-Cell Capture. Adv Healthc Mater 4:838-43 (2015). PubMed: 25645204
  • He TL  et al. The c-Myc-LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer. Med Oncol 32:187 (2015). IHC ; Human . PubMed: 26021472
  • Derenzini E  et al. Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma. Oncotarget 6:6553-69 (2015). IF . PubMed: 25544753
  • Simons BW  et al. A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression. J Pathol 235:478-89 (2015). IHC ; Mouse . PubMed: 25348195
  • Li S  et al. Regulation of c-Myc protein stability by proteasome activator REG?. Cell Death Differ 22:1000-11 (2015). PubMed: 25412630
  • Lee JG & Wu R Erlotinib-cisplatin combination inhibits growth and angiogenesis through c-MYC and HIF-1a in EGFR-mutated lung cancer in vitro and in vivo. Neoplasia 17:190-200 (2015). WB ; Mouse, Human . PubMed: 25748238
  • Carey CD  et al. Molecular classification of MYC-driven B-cell lymphomas by targeted gene expression profiling of fixed biopsy specimens. J Mol Diagn 17:19-30 (2015). IHC ; Human . PubMed: 25468432
  • Xiang Y  et al. Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. J Clin Invest 125:2293-306 (2015). IHC . PubMed: 25915584
  • Zou Y  et al. Resveratrol inhibits canonical Wnt signaling in human MG-63 osteosarcoma cells. Mol Med Rep 12:7221-6 (2015). WB, ICC/IF ; Human . PubMed: 26398440
  • Lawson DA  et al. Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells. Nature 526:131-5 (2015). IHC-P ; Human . PubMed: 26416748
  • Morgado-Palacin L  et al. Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis. Cell Rep 13:712-22 (2015). IHC-P ; Mouse . PubMed: 26489471
  • Siegfried JM  et al. Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome. Neoplasia 17:817-25 (2015). IHC-P ; Human . PubMed: 26678909
  • Sun XX  et al. The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc. Proc Natl Acad Sci U S A 112:3734-9 (2015). PubMed: 25775507
  • Massari F  et al. Prognostic Value of Beta-Tubulin-3 and c-Myc in Muscle Invasive Urothelial Carcinoma of the Bladder. PLoS One 10:e0127908 (2015). IHC-P ; Human . PubMed: 26046361
  • Mahmoud AZ  et al. Scoring of MYC protein expression in diffuse large B-cell lymphomas: concordance rate among hematopathologists. Mod Pathol 28:545-51 (2015). IHC-P ; Human . PubMed: 25431238
  • Barfeld SJ  et al. Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer. Oncotarget 6:12587-602 (2015). WB ; Human . PubMed: 25869206
  • Shokhirev MN  et al. A multi-scale approach reveals that NF-?B cRel enforces a B-cell decision to divide. Mol Syst Biol 11:783 (2015). ICC/IF ; Mouse . PubMed: 25680807
  • Tran D  et al. Functional genomics analysis reveals a MYC signature associated with a poor clinical prognosis in liposarcomas. Am J Pathol 185:717-28 (2015). IHC ; Human . PubMed: 25622542
  • Huang S  et al. Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy. J Cell Mol Med 19:608-19 (2015). WB . PubMed: 25583328
  • Kozono D  et al. Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression. Proc Natl Acad Sci U S A 112:E4055-64 (2015). IHC-P ; Mouse . PubMed: 26159421
  • Renaud SJ  et al. OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc Natl Acad Sci U S A 112:E6175-84 (2015). IHC-P, ICC/IF . PubMed: 26504231
  • Lu TX  et al. Epstein-Barr virus positive diffuse large B-cell lymphoma predict poor outcome, regardless of the age. Sci Rep 5:12168 (2015). IHC ; Human . PubMed: 26202875
  • Nowak DG  et al. MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discov 5:636-51 (2015). PubMed: 25829425
  • Cattoglio C  et al. Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. Proc Natl Acad Sci U S A 112:E2317-26 (2015). PubMed: 25901318
  • Xie CM  et al. Erbin is a novel substrate of the Sag-ßTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol 209:721-37 (2015). PubMed: 26056141
  • Shi J  et al. Deubiquitinase USP47/UBP64E Regulates ß-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling. Mol Cell Biol 35:3301-11 (2015). PubMed: 26169834
  • Bhusari S  et al. Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice. Toxicol Pathol 43:1114-26 (2015). PubMed: 26289556
  • Amaya CN & Bryan BA Enrichment of the embryonic stem cell reprogramming factors Oct4, Nanog, Myc, and Sox2 in benign and malignant vascular tumors. BMC Clin Pathol 15:18 (2015). PubMed: 26412983
  • Lee KS  et al. c-MYC Copy-Number Gain Is an Independent Prognostic Factor in Patients with Colorectal Cancer. PLoS One 10:e0139727 (2015). PubMed: 26426996
  • Chen J  et al. Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells. Mar Drugs 13:6259-73 (2015). PubMed: 26445050
  • Venant H  et al. The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo. Mol Cancer Ther 14:2744-52 (2015). PubMed: 26494858
  • Zhu YX  et al. RNA interference screening identifies lenalidomide sensitizers in multiple myeloma, including RSK2. Blood 125:483-91 (2015). PubMed: 25395420
  • Gajula RP  et al. Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells. Neoplasia 17:16-31 (2015). Human . PubMed: 25622896
  • González-Prieto R  et al. c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4. Cell Cycle 14:1859-72 (2015). PubMed: 25895136
  • Kim JS  et al. The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling. Endocrinology 155:3262-73 (2014). WB ; Human . PubMed: 24926821
  • Sabò A  et al. Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Nature 511:488-92 (2014). WB . PubMed: 25043028
  • Wiegering A  et al. E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts. Neoplasia 16:972-81 (2014). WB ; Human . PubMed: 25425971
  • Huang W  et al. C-MYC overexpression predicts aggressive transformation and a poor outcome in mucosa-associated lymphoid tissue lymphomas. Int J Clin Exp Pathol 7:5634-44 (2014). IHC ; Human . PubMed: 25337204
  • Guo H  et al. Post-translational glycoprotein modifications regulate colon cancer stem cells and colon adenoma progression in Apc(min/+) mice through altered Wnt receptor signaling. J Biol Chem 289:31534-49 (2014). PubMed: 25274627
  • Miyata-Takata T  et al. A case of diffuse large B-cell lymphoma transformed from primary duodenal follicular lymphoma. Pathol Int 64:527-32 (2014). PubMed: 25186289
  • Popovic R  et al. Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation. PLoS Genet 10:e1004566 (2014). WB ; Human . PubMed: 25188243
  • Harashima N  et al. Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon-ß-mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system. Mol Cancer 13:217 (2014). PubMed: 25227113
  • Turakhia SK  et al. Aggressive B-cell lymphomas with translocations involving BCL6 and MYC have distinct clinical-pathologic characteristics. Am J Clin Pathol 142:339-46 (2014). PubMed: 25125624
  • Molina TJ  et al. Young patients with non-germinal center B-cell-like diffuse large B-cell lymphoma benefit from intensified chemotherapy with ACVBP plus rituximab compared with CHOP plus rituximab: analysis of data from the Groupe d'Etudes des Lymphomes de l'Adulte/lymphoma study association phase III trial LNH 03-2B. J Clin Oncol 32:3996-4003 (2014). IHC-P ; Human . PubMed: 25385729
  • Ferrari de Andrade L  et al. Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Res 74:7298-308 (2014). WB ; Mouse . PubMed: 25351955
  • Saborowski M  et al. A modular and flexible ESC-based mouse model of pancreatic cancer. Genes Dev 28:85-97 (2014). WB ; Mouse . PubMed: 24395249
  • Toon CW  et al. Immunohistochemistry for myc predicts survival in colorectal cancer. PLoS One 9:e87456 (2014). IHC-P ; Human . PubMed: 24503701
  • Cho H  et al. RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis. Cancer Discov 4:318-33 (2014). PubMed: 24444712
  • Sanz-Moreno A  et al. Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation. PLoS One 9:e89187 (2014). IF, IHC ; Mouse . PubMed: 24586582
  • Xie Y  et al. p53 expression is a strong marker of inferior survival in de novo diffuse large B-cell lymphoma and may have enhanced negative effect with MYC coexpression: a single institutional clinicopathologic study. Am J Clin Pathol 141:593-604 (2014). Human . PubMed: 24619762
  • Qi WL  et al. Involvement of RbAp48 in erythroid differentiation of murine erythroleukemia cells induced by sodium butyrate. Oncol Lett 7:1785-1789 (2014). WB ; Human . PubMed: 24932233
  • van der Meer R  et al. RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibition. Clin Cancer Res 20:3211-21 (2014). PubMed: 24771642
  • Farrell AS  et al. Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer. Mol Cancer Res 12:924-39 (2014). WB, ChIP . PubMed: 24667985
  • Janghorban M  et al. Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer. Proc Natl Acad Sci U S A 111:9157-62 (2014). ChIP . PubMed: 24927563
  • Bellas C  et al. Immunohistochemical and molecular characteristics with prognostic significance in diffuse large B-cell lymphoma. PLoS One 9:e98169 (2014). IHC-P ; Human . PubMed: 24887414
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