製品の概要

  • 製品名
    BzATP triethylammonium salt
  • 製品の詳細
    Potent, prototypic P2X7 agonist. P2 agonist.
  • 生理活性の詳細
    Prototypic P2X7 receptor agonist, showing 5-10 fold greater potency than ATP (pEC50 = 6.5). Also exhibits activity at other P2 receptors (EC50 values are 5 and 63 μM at P2X3 and P2Y11, respectively). Shows high potency at P2X1 receptor (pEC50 = 8.7). Potent activator of cAMP production.
  • 精製度
    > 94%

製品の特性

参考文献

This product has been referenced in:
  • Jacobson KA  et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal 5:75-89 (2009). Read more (PubMed: 18600475) »
  • Michel AD  et al. Serum constituents can affect 2'-& 3'-O-(4-benzoylbenzoyl)-ATP potency at P2X(7) receptors. Br J Pharmacol 132:1501-8 (2001). Read more (PubMed: 11264244) »
  • Boué-Grabot E  et al. Unique functional properties of a sensory neuronal P2X ATP-gated channel from zebrafish. J Neurochem 75:1600-7 (2000). Read more (PubMed: 10987841) »
  • Conigrave AD  et al. Pharmacological profile of a novel cyclic AMP-linked P2 receptor on undifferentiated HL-60 leukemia cells. Br J Pharmacol 124:1580-5 (1998). Read more (PubMed: 9723974) »
  • Bennett CE Fasciola hepatica: development of caecal epithelium during migration in the mouse. Exp Parasitol 37:426-41 (1975). Read more (PubMed: 1126424) »

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