製品の概要

  • 製品名Anti-BVES antibody
    BVES 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to BVES
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Recombinant fragment: YSLNDPTLND KKAKKLEHQL SLCTQISMLE MRNSIASSSD SDDGLHQFLR GTSSMSSLHV SSPHQRASAK MKPIEEGAED DDDVFEPASP NTLKVHQLP, corresponding to amino acids 262-360 of human BVES (NP_009004) with a 26 kDa tag.

  • ポジティブ・コントロール
    • IMR-32 cell lysate; recombinant tagged fragment of human BVES.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 41 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading.
  • 組織特異性Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle.
  • 配列類似性Belongs to the popeye family.
  • 細胞内局在Lateral cell membrane. Cell junction > tight junction. Membrane. Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Blood vessel epicardial substance antibody
    • Bves antibody
    • hBVES antibody
    • MGC42413 antibody
    • POP 1 antibody
    • POP1 antibody
    • POPD1_HUMAN antibody
    • POPDC 1 antibody
    • POPDC1 antibody
    • Popeye domain containing 1 antibody
    • Popeye domain containing protein 1 antibody
    • Popeye domain-containing protein 1 antibody
    • Popeye protein 1 antibody
    see all

Anti-BVES antibody 画像

  • Anti-BVES antibody (ab77639) at 1/500 dilution + Recombinant tagged fragment of human BVES (the immunogen) at 0.2 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 41 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • Anti-BVES antibody (ab77639) at 1/500 dilution + IMR-32 cell lysate at 25 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 41 kDa
    Observed band size : 41 kDa

Anti-BVES antibody (ab77639) 使用論文

ab77639 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. Unfortunately we have not tested this antibody in Immunofluorescence, and I am afraid we do not have any other BVES antibody suitable for this technique in our catalogue. The fact that it has not been tested does n...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"