製品の概要

  • 製品名Anti-BSND antibody
    BSND 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to BSND
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-320 of Human BSND (NP_476517.1)

  • ポジティブ・コントロール
    • 293 cell lysate Transfected 293T cell lysate Human kidney tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa.
IHC-P Use a concentration of 3 µg/ml.

ターゲット情報

  • 機能Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
  • 組織特異性Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.
  • 関連疾患Bartter syndrome 4A
  • 細胞内局在Cell membrane. Cytoplasm. A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BART antibody
    • Bartter syndrome infantile with sensorineural deafness antibody
    • Bartter syndrome, infantile, with sensorineural deafness (Barttin) antibody
    • Barttin antibody
    • Bsnd antibody
    • BSND_HUMAN antibody
    • deafness, autosomal recessive 73 antibody
    • DFNB 73 antibody
    • DFNB73 antibody
    see all

Anti-BSND antibody 画像

  • Anti-BSND antibody (ab88518) at 1 µg/ml + 293 cell lysate at 50 µg

    Secondary
    Goat anti-mouse IgG at 1/5000 dilution

    Predicted band size : 35 kDa
  • All lanes : Anti-BSND antibody (ab88518) at 1 µg/ml

    Lane 1 : BSND transfected 293T cell lysate
    Lane 2 : Untransfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-mouse IgG at 1/5000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
  • Immunoperoxidase staining of human kidney tissue labelled with ab88518 at 3 µg/ml

Anti-BSND antibody (ab88518) 使用論文

ab88518 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab88518.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"