製品の概要

  • 製品名Anti-BSND antibody
    BSND 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BSND
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 211-260 (PNASPHDREE ACSPQQEPQG CRCPLDRFQD FALIDAPTLE DEPQEGQQWE) of Human BSND (NP_476517).

  • ポジティブ・コントロール
    • Human fetal heart lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108150 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
  • 組織特異性Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.
  • 関連疾患Bartter syndrome 4A
  • 細胞内局在Cell membrane. Cytoplasm. A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BART antibody
    • Bartter syndrome infantile with sensorineural deafness antibody
    • Bartter syndrome, infantile, with sensorineural deafness (Barttin) antibody
    • Barttin antibody
    • Bsnd antibody
    • BSND_HUMAN antibody
    • deafness, autosomal recessive 73 antibody
    • DFNB 73 antibody
    • DFNB73 antibody
    see all

Anti-BSND antibody 画像

  • Anti-BSND antibody (ab108150) at 1 µg/ml + Human fetal heart lysate at 10 µg

    Predicted band size : 35 kDa

Anti-BSND antibody (ab108150) 使用論文

ab108150 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"