製品の概要

  • 製品名Anti-BRSK1 antibody
    BRSK1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BRSK1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to 28 internal sequence amino acids of Human BRSK1 (BAB47440.1).

  • ポジティブ・コントロール
    • Human Brain Cortex tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab117251 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 87 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.
  • 組織特異性Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
  • 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.
    Contains 1 protein kinase domain.
    Contains 1 UBA domain.
  • 細胞内局在Cytoplasm. Nucleus. Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BR serine/threonine kinase 1 antibody
    • BR serine/threonine protein kinase 1 antibody
    • BR serine/threonine-protein kinase 1 antibody
    • Brain selective kinase 1 antibody
    • Brain-specific serine/threonine-protein kinase 1 antibody
    • BRSK 1 antibody
    • Brsk1 antibody
    • BRSK1_HUMAN antibody
    • FLJ43009 antibody
    • hSAD1 antibody
    • KIAA1811 antibody
    • Protein kinase SAD1A antibody
    • SAD 1 antibody
    • SAD1 antibody
    • SAD1 homolog antibody
    • SAD1 kinase antibody
    • SAD1A antibody
    • SADB antibody
    • SadB kinase short isoform antibody
    • Serine/threonine kinase SAD B antibody
    • Serine/threonine-protein kinase SAD-B antibody
    • Synapses of Amphids Defective homolog antibody
    see all

Anti-BRSK1 antibody 画像

  • ab117251, at 5 µg/ml, staining BRSK1 in Formalin-fixed, Paraffin-embedded Human brain cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-BRSK1 antibody (ab117251) 使用論文

ab117251 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"