製品の概要

  • 製品名BRL 54443
  • 製品の詳細
    Selective agonist at 5-HT1E and 5-HT1F receptors
  • 生理活性の詳細Potent, high affinity and selective agonist at 5-HT1E/1F receptors (pKi values are 8.7 and 8.9, respectively). Displays >30-fold selectivity for human 5-HT over dopamine receptors (pKi values are 7.2 (5-HT1A), 6.9 (5-HT1B), 7.2 (5-HT1D), 5.9 (5-HT2A), 7.0 (5-HT2B), 6.5 (5-HT2C), 6.3 (D2) and 6.2 (D3)).
  • 精製度> 99%

製品の特性

  • 体系名5-Hydroxy-3-(1-methylpiperidin-4-yl)-1H-indole
  • 分子量230.31
  • 構造式Chemical Structure
  • 分子式C14H18N2O
  • CAS 番号57477-39-1
  • PubChem 登録番号2438
  • 保存方法Store at +4°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性Soluble in DMSO to 50 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記CN1CCC(CC1)c2cnc3ccc(O)cc23
  • 由来

    Synthetic

  • 研究分野

    BRL 54443 (ab120627) 使用論文

    ab120627 has not yet been referenced specifically in any publications.

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