BRL 44408 maleate, alpha2A adrenoceptor antagonist (ab120806)
Key features and details
- Selective α2A adrenoceptor antagonist
- CAS Number: 681806-46-2
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
BRL 44408 maleate, alpha2A adrenoceptor antagonist -
製品の詳細
Selective α2A adrenoceptor antagonist -
生理活性の詳細
Selective α2A adrenoceptor antagonist (Ki values are 5.68 and 651 nM for α2A and α2B, respectively). Centrally active following subcutaneous administration. Demonstrates antidepressant and analgesic activity.
-
精製度
> 99% -
CAS 番号
681806-46-2 -
構造式
製品の特性
-
体系名
2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate -
分子量
331.37 -
分子式
C13H17N3.C4H4O4 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
由来
Synthetic
-
研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120806 は 1 報の論文で使用されています。
- Li Q et al. Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence. Front Immunol 12:823935 (2021). PubMed: 35140713