製品の概要

  • 製品名
    BRL 15572 monohydrochloride
  • 製品の詳細
    Selective 5-HT1D receptor antagonist
  • 生理活性の詳細
    Selective 5-HT1D antagonist. 60-fold higher affinity for 5-HT1D (pKi = 7.9) over 5-HT1B receptors. Brain penetrant.
  • 精製度
    > 98%

製品の特性

参考文献

This product has been referenced in:
  • Granados-Soto V  et al. The role of peripheral 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F serotonergic receptors in the reduction of nociception in rats. Neuroscience 165:561-8 (2010). Read more (PubMed: 19837141) »
  • Price GW  et al. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol 356:312-20 (1997). Read more (PubMed: 9303567) »
  • Schlicker E  et al. Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors. Naunyn Schmiedebergs Arch Pharmacol 356:321-7 (1997). Read more (PubMed: 9303568) »

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