製品の概要

  • 製品名Anti-BRIT1 antibody
    BRIT1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to BRIT1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: ATSSCVTSAP EEALRCCRQA GKEDACPEGN GFSYTIEDPA LPKGHDDDLT PLEGSLEEMK EAVGLKSTQN KGTTSKISNS SEGEAQSEH, corresponding to amino acids 399-488 of Human BRIT1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57751 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
    • 組織特異性Expressed in fetal brain, liver and kidney.
    • 関連疾患Defects in MCPH1 are the cause of microcephaly primary type 1 (MCPH1) [MIM:251200]; also known as true microcephaly or microcephaly vera. Microcephaly is defined as a head circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. Despite this marked reduction in size, the gyral pattern is relatively well preserved, with no major abnormality in cortical architecture. Primary microcephaly is further defined by the absence of other syndromic features or significant neurological deficits. This entity is inherited as autosomal recessive trait.
    • 配列類似性Contains 3 BRCT domains.
    • 細胞内局在Cytoplasm > cytoskeleton > centrosome.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BRCT repeat inhibitor of TERT expression 1 antibody
      • BRIT 1 antibody
      • FLJ12847 antibody
      • Hypothetical protein FLJ12847 antibody
      • MCPH 1 antibody
      • MCPH1 antibody
      • MCPH1_HUMAN antibody
      • MCT antibody
      • Microcephalin 1 antibody
      • Microcephalin antibody
      • Microcephaly primary autosomal recessive 1 antibody
      see all

    Anti-BRIT1 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57751 BRIT1 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    Anti-BRIT1 antibody (ab57751) 使用論文

    ab57751 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57751.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"