製品の概要

  • 製品名
    Anti-BRCC2 antibody
  • 製品の詳細
    Mouse monoclonal to BRCC2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 2-109 of Human BRCC2

  • 特記事項

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Functions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death.
    • 組織特異性
      Ubiquitously expressed.
    • 細胞内局在
      Cytoplasm. Mitochondrion. Lower abundance in mitochondrion than in cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BH3-like motif containing, cell death inducer antibody
      • BH3-like motif-containing cell death inducer antibody
      • BLID antibody
      • BLID_HUMAN antibody
      • BRCC2 antibody
      • breast cancer cell 2 antibody
      • Breast cancer cell protein 2 antibody
      see all

    Anti-BRCC2 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57813 BRCC2 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    プロトコール

    Anti-BRCC2 antibody (ab57813) 使用論文

    This product has been referenced in:
    • Li X  et al. BRCC2 inhibits breast cancer cell growth and metastasis in vitro and in vivo via downregulating AKT pathway. Cell Death Dis 4:e757 (2013). Read more (PubMed: 23928696) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab57813.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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