製品の概要

  • 製品名Anti-Bok antibody
    Bok 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Bok
  • 特異性The antibody detects the 18 kDa recombinant rat BOK expressed in E.coli.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Synthetic peptide: corresponding to amino acids 41-61 of Bok

  • 特記事項


    Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Thimerosal (merthiolate)
    Constituents: 50% Glycerol, 1% BSA, PBS, pH 7.2
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 一次抗体 備考Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab2304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml.

ターゲット情報

  • 機能May play a role in apoptosis.
  • 組織特異性Expressed in brain, liver, appendix and lymphoid tissues.
  • 配列類似性Belongs to the Bcl-2 family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Bcl 2 related ovarian killer protein antibody
    • Bcl-2-like protein 9 antibody
    • Bcl-2-related ovarian killer protein antibody
    • BCL2 related ovarian killer antibody
    • Bcl2-L-9 antibody
    • BCL2L9 antibody
    • BOK antibody
    • BOK_HUMAN antibody
    • BOKL antibody
    • Hbok antibody
    • MGC4631 antibody
    see all

Anti-Bok antibody (ab2304) 使用論文

This product has been referenced in:
  • Siu PM & Alway SE Mitochondria-associated apoptotic signalling in denervated rat skeletal muscle. J Physiol 565:309-23 (2005). WB ; Rat . Read more (PubMed: 15774533) »

See 1 Publication for this product

Product Wall

The supplier of ab2304 has informed me that the immunogen is not available to purchase. If you have any more questions, please contact us again.

Ab2304 is an antibody that we do not make in-house and instead source from another company. I have enquired with the supplier of ab2304 to see if it is an option for you to purchase it. As soon as I hear back from the supplier I will let you know.

The immunogen is a.a. 41-61 of rat Bok.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"