製品の概要

  • 製品名Anti-BOB1 antibody
    BOB1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BOB1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    A synthetic peptide from C-terminus of human BOB1.

  • ポジティブ・コントロール
    • Raji cells. Tonsil.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab52103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration.
IHC-P 1/50. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

ターゲット情報

  • 機能Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
  • 組織特異性B-cell specific.
  • 関連疾患Note=A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.
  • 配列類似性Belongs to the POU2AF1 family.
  • 翻訳後修飾Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B cell Oct binding protein 1 antibody
    • B cell specific coactivator OBF 1 antibody
    • B cell specific coactivator OBF1 antibody
    • B-cell-specific coactivator OBF-1 antibody
    • BOB 1 antibody
    • BOB-1 antibody
    • OBF 1 antibody
    • OBF1 antibody
    • OBF1_HUMAN antibody
    • OCA B antibody
    • OCA-B antibody
    • OCAB antibody
    • OCT binding factor 1 antibody
    • OCT-binding factor 1 antibody
    • POU class 2 associating factor 1 antibody
    • POU domain class 2 associating factor 1 antibody
    • POU domain class 2-associating factor 1 antibody
    • Pou2af1 antibody
    see all

Anti-BOB1 antibody 画像

  • Human tonsil stained with ab52103 1:50 dilution by Immunohistochemistry (Formalin/paraffin).
  • Anti-BOB1 antibody (ab52103) at 1/25 dilution + lysate prepared from Ramos cells

    Observed band size : 35 kDa (why is the actual band size different from the predicted?)

Anti-BOB1 antibody (ab52103) 使用論文

ab52103 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"