製品の概要

  • 製品名Anti-BOB1 antibody
    BOB1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to BOB1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    YTEYVPHEAVSCP

    , corresponding to internal sequence amino acids 105-117 of Human BOB1 (NP_006226.2).

  • ポジティブ・コントロール
    • HEK293 transiently expressing full-length Human BOB1 (myc and DYKDDDDK tagged).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab118389 is purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab118389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 27 kDa).

ターゲット情報

  • 機能Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
  • 組織特異性B-cell specific.
  • 関連疾患Note=A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.
  • 配列類似性Belongs to the POU2AF1 family.
  • 翻訳後修飾Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B cell Oct binding protein 1 antibody
    • B cell specific coactivator OBF 1 antibody
    • B cell specific coactivator OBF1 antibody
    • B-cell-specific coactivator OBF-1 antibody
    • BOB 1 antibody
    • BOB-1 antibody
    • OBF 1 antibody
    • OBF1 antibody
    • OBF1_HUMAN antibody
    • OCA B antibody
    • OCA-B antibody
    • OCAB antibody
    • OCT binding factor 1 antibody
    • OCT-binding factor 1 antibody
    • POU class 2 associating factor 1 antibody
    • POU domain class 2 associating factor 1 antibody
    • POU domain class 2-associating factor 1 antibody
    • Pou2af1 antibody
    see all

Anti-BOB1 antibody 画像

  • Lane 1 : Anti-BOB1 antibody (ab118389) at 0.5 µg/ml
    Lane 2 : Anti-BOB1 antibody (ab118389) at 1 mg/ml
    Lane 3 : Anti-DYKDDDDK Tag antibody at 1/3000 dilution

    Lane 1 : HEK293 cell lyaste, transfected with full-length Human BOB1 (myc and DYKDDDDK tagged)
    Lane 2 : HEK293 cell lyaste, mock transfected
    Lane 3 : HEK293 cell lyaste, transfected with full-length Human BOB1 (myc and DYKDDDDK tagged)

    Lysates/proteins at 10 µg per lane.


    Predicted band size : 27 kDa

Anti-BOB1 antibody (ab118389) 使用論文

ab118389 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"