製品の概要

  • 製品名Anti-BNP/ProBNP antibody
    BNP/ProBNP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BNP/ProBNP
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 to the C-terminus of Human BNP/ProBNP.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Human Heart tissue lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab105181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 18 kDa (predicted molecular weight: 15 kDa).

ターゲット情報

  • 機能Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 組織特異性Brain and also in atria, but at much lower levels than ANP.
  • 配列類似性Belongs to the natriuretic peptide family.
  • 翻訳後修飾The brain natriuretic peptide 32 form is cleaved at Pro-104 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANFB_HUMAN antibody
    • BNP antibody
    • BNP(1-32) antibody
    • BNP(5-29) antibody
    • BNP-32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Gamma-brain natriuretic peptide antibody
    • Natriuretic peptide B antibody
    • Natriuretic peptide precursor B antibody
    • Natriuretic protein antibody
    • nppb antibody
    see all

Anti-BNP/ProBNP antibody 画像

  • All lanes : Anti-BNP/ProBNP antibody (ab105181) at 1 µg/ml

    Lane 1 : Human heart tissue lysate - total protein (ab29431)
    Lane 2 : Human heart tissue lysate - total protein (ab29431) with Immunising peptide at 1 µg/ml

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 15 kDa
    Observed band size : 18 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 108 kDa,73 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 6 minutes

Anti-BNP/ProBNP antibody (ab105181) 使用論文

ab105181 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab105181.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"