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RabMAb

Anti-BNP 抗体 [EPR3735] (ab92500)

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製品の概要

  • 製品名
    Anti-BNP antibody [EPR3735]
    BNP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR3735] to BNP
  • アプリケーション
    適用あり: WBmore details
    適用なし: IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human BNP.

  • ポジティブ･コントロール
    • Human plasma and fetal heart lysate.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab92500 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: 1/2000 - 1/20000. Detects a band of approximately 30 kDa (predicted molecular weight: 15 kDa).

    Is unsuitable for IHC-P or IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • ターゲット情報

    • 関連性
      Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
    • 細胞内局在
      Secreted
    • 参照データベース
      • 別名
        • BNP(1-28) antibody
        • BNP(1-29) antibody
        • BNP(1-30) antibody
        • BNP(1-32) antibody
        • BNP(2-31) antibody
        • BNP(3-29) antibody
        • BNP(3-30) antibody
        • BNP(3-32) antibody
        • BNP(4-27) antibody
        • BNP(4-29) antibody
        • BNP(4-30) antibody
        • BNP(4-31) antibody
        • BNP(4-32) antibody
        • BNP(5-29) antibody
        • BNP(5-31) antibody
        • BNP(5-32) antibody
        • Brain natriuretic peptide 32 antibody
        • Brain type natriuretic peptide antibody
        • Gamma brain natriuretic peptide antibody
        • Natriuretic peptide B antibody
        • Natriuretic peptide precursor B antibody
        • natriuretic peptide, brain type antibody
        • Natriuretic peptides B antibody
        • natriuretic protein antibody
        • NPPB antibody
        see all

      Anti-BNP antibody [EPR3735] 画像

      • Western blot - BNP antibody [EPR3735] (ab92500)
        Western blot - BNP antibody [EPR3735] (ab92500)
        All lanes : Anti-BNP antibody [EPR3735] (ab92500) at 1/2000 dilution

        Lane 1 : Human plasma
        Lane 2 : Human fetal heart lysate

        Lysates/proteins at 10 µg per lane.

        Secondary
        goat anti-rabbit HRP at 1/2000 dilution

        Predicted band size : 15 kDa
        Observed band size : 30 kDa (why is the actual band size different from the predicted?)

      プロトコール

      Anti-BNP antibody [EPR3735] (ab92500) 使用論文

      ab92500 has not yet been referenced specifically in any publications.

      ab92500 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      Product Wall

      ab92500 の abreview を投稿する ab92500 に関する問い合わせをする

      2 Abreviews or Q&A

      10
      Votes: Highest First

      Thank you very much. I think antibodies ab92500 and ab47003 will fit to our purpose. So, we are interested in buying them. Could you please send us a quotation for the purchase of both antibodies?

      I look forward to receiving your reply.

      Thank you for your reply and your interest in Abcam antibodies.

      For a quotation, please contact our Australian distributor Sapphire Bioscience Pty Ltd.
      Their contact details are :
      126 Cope Street
      Waterloo - NSW
      2017
      ...

      Read More

      Dear Sir/Madam,

      I am working as a Research Associate at the Mawson Institute (University of South Australia).We are working onthe detection ofbrain natriuretic peptide (BNP) and troponin I.Regarding BNP, currently we are working with a glyco...

      Read More

      Thank you for contacting us.

      proBNP:

      As shown on the attached file (ab92500 v proBNP.pdf), ab92500seems to be suitable for your work as it would bind to the proBNP at a different region than the Mouse antibody that binds the region ...

      Read More

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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