製品の概要

  • 製品名Anti-BMPER antibody
    BMPER 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BMPER
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region of human BMPER

  • ポジティブ・コントロール
    • Fetal heart lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab75183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 76 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.
  • 組織特異性Highly expressed in lung, and brain and also in primary chondrocytes.
  • 関連疾患Defects in BMPER are the cause of diaphanospondylodysostosis (DSD) [MIM:608022]. A rare, recessively inherited, perinatal lethal skeletal disorder. The primary skeletal characteristics of the phenotype include a small chest, abnormal vertebral segmentation, and posterior rib gaps containing incompletely differentiated mesenchymal tissue. Consistent craniofacial features include ocular hypertelorism, epicanthal folds, a depressed nasal bridge with a short nose, and low-set ears. The most commonly described extraskeletal finding is nephroblastomatosis with cystic kidneys, but other visceral findings have been described in some cases.
  • 配列類似性Contains 1 TIL (trypsin inhibitory-like) domain.
    Contains 5 VWFC domains.
    Contains 1 VWFD domain.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BMP binding endothelial regulator antibody
    • BMP binding endothelial regulator precursor protein antibody
    • BMP-binding endothelial regulator protein antibody
    • BMPER antibody
    • BMPER_HUMAN antibody
    • Bone morphogenetic protein binding endothelial cell precursor derived regulator antibody
    • Bone morphogenetic protein-binding endothelial cell precursor-derived regulator antibody
    • CRIM3 antibody
    • Crossveinless 2 antibody
    • CV 2 antibody
    • CV2 antibody
    • hCV2 antibody
    • Protein crossveinless 2 antibody
    • Protein crossveinless-2 antibody
    see all

Anti-BMPER antibody 画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling BMPER with ab75183 at 5µg/ml.

  • Anti-BMPER antibody (ab75183) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 76 kDa
    Observed band size : >90 kDa (why is the actual band size different from the predicted?)

Anti-BMPER antibody (ab75183) 使用論文

ab75183 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab75183.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"