製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to BMP7
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Rat, Chicken, Human
  • 免疫原

    Synthetic peptide corresponding to Human BMP7 (C terminal).
    Database link: NM_001719

  • ポジティブ・コントロール
    • Rat kidney tissue; Human kidney cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報
    IHC-P: 1/50 - 1/200.
    WB: 1/200 - 1/1000. Predicted molecular weight: 49 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
    • 組織特異性
      Expressed in the kidney and bladder. Lower levels seen in the brain.
    • 配列類似性
      Belongs to the TGF-beta family.
    • 発生段階
      Expressed in the developing eye, brain and ear during embryogenesis.
    • 翻訳後修飾
      Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BMP 7 antibody
      • BMP-7 antibody
      • Bmp7 antibody
      • BMP7_HUMAN antibody
      • Bone morphogenetic protein 7 antibody
      • Bone morphogenic protein 7 antibody
      • Eptotermin alfa antibody
      • OP 1 antibody
      • OP-1 antibody
      • OP1 antibody
      • Osteogenic protein 1 antibody
      see all

    画像

    • ab93636, at 1/100 dilution, staining secreted BMP7 in formalin-fixed, paraffin-embedded rat kidney tissue by Immunohistochemistry.
    • Anti-BMP7 antibody (ab93636) at 1/200 dilution + Human kidney cell lysate

      Predicted band size: 49 kDa

    参考文献

    This product has been referenced in:
    • Zhang Y  et al. Effects of imposed defocus of opposite sign on temporal gene expression patterns of BMP4 and BMP7 in chick RPE. Exp Eye Res 109:98-106 (2013). Read more (PubMed: 23428741) »

    See 1 Publication for this product

    レビューと Q&A

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    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Chicken Tissue lysate - whole (retina, RPE, choroid)
    Loading amount
    20 µg
    Specification
    retina, RPE, choroid
    Gel Running Conditions
    Reduced Denaturing (NuPAGE 4-12% Bis-Tris Gel)
    Blocking step
    (agent) for 30 minute(s) · Concentration: 100% · Temperature: 25°C
    Username

    Yan Zhang

    Verified customer

    投稿 Feb 28 2012

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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