製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to BMP10
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 360-421 of BMP10 (Human)

  • ポジティブ・コントロール
    • H1299 cell lysate

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96593 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.

ターゲット情報

  • 機能
    Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
  • 配列類似性
    Belongs to the TGF-beta family.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BMP-10 antibody
    • Bmp10 antibody
    • BMP10_HUMAN antibody
    • Bone morphogenetic protein 10 antibody
    • Bone morphogenetic protein 10 preproprotein antibody
    • MGC126783 antibody
    • OTTHUMP00000159973 antibody
    see all

画像

  • Anti-BMP10 antibody (ab96593) at 1/500 dilution (10% SDS PAGE) + H1299 whole cell lysate at 30 µg

    Predicted band size : 48 kDa

プロトコール

参考文献

ab96593 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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