Anti-Blooms Syndrome Protein Blm 抗体 (ab70309)

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製品の概要

  • 製品名
    Anti-Blooms Syndrome Protein Blm antibody
    Blooms Syndrome Protein Blm 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Blooms Syndrome Protein Blm
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to a region between residues 50 and 100 of mouse Blooms Syndrome Protein Blm. ( NP_031576.2 )

  • ポジティブ･コントロール
    • NIH3T3 whole cell lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab70309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 1 µg/mg of lysate.
  • 追加情報
    Is unsuitable for WB.

    • ターゲット情報

    • 機能
      Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.
    • 関連疾患
      Defects in BLM are the cause of Bloom syndrome (BLM) [MIM:210900]. BLM is an autosomal recessive disorder characterized by proportionate pre- and postnatal growth deficiency, sun-sensitive telangiectatic hypo- and hyperpigmented skin, predisposition to malignancy, and chromosomal instability.
    • 配列類似性
      Belongs to the helicase family. RecQ subfamily.
      Contains 1 helicase ATP-binding domain.
      Contains 1 helicase C-terminal domain.
      Contains 1 HRDC domain.
    • 翻訳後修飾
      Phosphorylated in response to DNA damage. Phosphorylation requires the FANCA-FANCC-FANCE-FANCF-FANCG protein complex, as well as the presence of RMI1.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
      • 別名
        • Blm antibody
        • BLM_HUMAN antibody
        • Bloom syndrome antibody
        • Bloom syndrome protein antibody
        • Bloom syndrome RecQ helicase like antibody
        • BS antibody
        • DNA helicase antibody
        • DNA helicase RecQ like type 2 antibody
        • MGC126616 antibody
        • MGC131618 antibody
        • MGC131620 antibody
        • RECQ 2 antibody
        • RECQ like antibody
        • RecQ like type 2 antibody
        • RecQ protein like 3 antibody
        • RecQ protein-like 3 antibody
        • RecQ-like type 2 antibody
        • RecQ2 antibody
        • RECQL 2 antibody
        • RECQL 3 antibody
        • RECQL2 antibody
        • RECQL3 antibody
        • type 2 antibody
        see all

      プロトコール

      参考文献

      ab70309 has not yet been referenced specifically in any publications.

      ab70309 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      レビューと Q&A

      レビューを送る 質問を送る

      2 reviews or Q&A

      10
      Votes: Highest First

      Hi,

      Thanks for your reply. I will be willing to purchase an aliquot of the ab135103 antibody. Please generate the discount code and I will submit an appropriate IF review based on the results obtained

      Best wishes

      DISCOUNT CODE: xxxxxxxx
      Expiration date: 22nd of December 2012

      I am very pleased to hear you would like to accept our offer and test ab135103 in IF wiht mouse samples. This code will give you: 1 freeprimary antibody of the value of ab135...

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      Inquiry: Hi I need a Bloom syndrome antibody to perform immunofluorescence and immunoprecipitaion reactions in NIH-3T3 mouse embryonic fibroblasts. I can see that your Anti-Blooms Syndrome Protein Blm antibody (ab70309) has been suggested to be used wi...

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      Thank you for contacting us and your interest in our products.

      As you have observed from the datasheet of the anti-Blooms Syndrome Protein Blm antibody (ab70309) this antibodycan beused with NIH3T3 whole cell lysate. However, we have only eve...

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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