製品の概要

  • 製品名Anti-Blood Group Wrb antibody [E6]
  • 製品の詳細
    Mouse monoclonal [E6] to Blood Group Wrb
  • 特異性ab50293 binds to Wrb, a composite blood group antigen resulting from the association between Glycophorin A and Band 3. The antibody (also cited as clone no. 7H12) binds to 9% of bone marrow nucleated cells in smears and tissue preparations using immunofluorescent microscopy or flow cytometry.
  • アプリケーション適用あり: Flow Cyt, Agglutination, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human thymus

  • ポジティブ・コントロール
    • Human erythrocytes (agglutination) and bone marrow nucleated cells (flow cytometry and indirect immunofluorescence)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab50293 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use at an assay dependent concentration. ab170192-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
Agglutination 1/10.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 関連性Wrb is a composite blood group antigen resulting from the association between Glycophorin A and Band 3. Wrb directly agglutinates erythrocytes, giving reduced deformability and inhibition of malarial parasite invasion (eg P. falciparum, P. knowles). The antigen is thought to be related to Glycophorin A/Band 3 interaction in the lipid bilayer.
  • 細胞内局在Cell Membrane and Nuclear
  • 参照データベース
  • 別名
    • CHD5 antibody
    • Congenital heart disease 5 protein antibody
    • Tryptophan rich basic protein antibody
    • WRB antibody

Anti-Blood Group Wrb antibody [E6] (ab50293) 使用論文

This product has been referenced in:
  • Telen MJ & Bolk TA Human red cell antigens. IV. The abnormal sialoglycoprotein of Gerbich-negative red cells. Transfusion 27:309-14 (1987). Read more (PubMed: 3603658) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab50293.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"