製品の概要

  • 製品名Anti-Blood Group Lewis x antibody [P12]
  • 製品の詳細
    Mouse monoclonal [P12] to Blood Group Lewis x
  • 特異性This antibody belongs to the BG-7 group and is specific for Lewis x (Type 2 Chain).
  • アプリケーション適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Fresh (non-cultured) placenta cell preparation (Human).

  • ポジティブ・コントロール
    • Human kidney tissue.
  • 特記事項


    Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis a, Lewis b, Lewis x, Lewis y, and precursor type 1 chain antigens. This antibody belongs to the BG-7 group and detects the Lewis x (type 2 chain) blood-group antigen, which is expressed in gastrointestinal tumors, and lung cancers. It is found in crypt cells, which represent the proliferative compartment of the colonic mucosa, and strong homogeneous immunostaining is observed in most metastases and invasive cancer cells.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーConstituents: 0.0268% PBS, 1% BSA
  • 精製度Tissue culture supernatant
  • 一次抗体 備考Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis a, Lewis b, Lewis x, Lewis y, and precursor type 1 chain antigens. This antibody belongs to the BG-7 group and detects the Lewis x (type 2 chain) blood-group antigen, which is expressed in gastrointestinal tumors, and lung cancers. It is found in crypt cells, which represent the proliferative compartment of the colonic mucosa, and strong homogeneous immunostaining is observed in most metastases and invasive cancer cells.
  • ポリ/モノモノクローナル
  • クローン名P12
  • アイソタイプIgM
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab3358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/40.
ICC/IF 1/200 - 1/400.

ターゲット情報

  • 別名
    • Le(x) antibody
    • Lewis x Blood Group antibody

Anti-Blood Group Lewis x antibody [P12] (ab3358) 使用論文

This product has been referenced in:
  • Shi CS  et al. Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response. Blood 112:3661-70 (2008). Read more (PubMed: 18711002) »
  • Nyström K  et al. Virus-induced transcriptional activation of host FUT genes associated with neo-expression of Ley in cytomegalovirus-infected and sialyl-Lex in varicella-zoster virus-infected diploid human cells. Glycobiology 17:355-66 (2007). Read more (PubMed: 17202152) »

See all 2 Publications for this product

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I can confirm that the storage temperature of our products can be found on the individual datasheets.

Short term storage is usually two weeks. If the products is not used within two weeks of purchase, we ...

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I can confirm that ab3358Blood Group Lewis x antibody [P12] is sold as tissue culture supernatant. I have requested that the datasheetisupdated so thisinformation is clearer. Unpurified antibodies, such as those s...

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Thank you for your enquiry. This antibody is tissue culture supernatant concentrated by ammonium sulfate precipitation. The concentration of our last lot was 180 ug/ml. We don't currently have any stock of this antibody, so the concentration may ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"