Anti-Blood Group A Antigen 抗体 [HE-193] (ab2521)

製品の概要

  • 製品名
    Anti-Blood Group A Antigen antibody [HE-193]
    Blood Group A Antigen 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [HE-193] to Blood Group A Antigen
  • 特異性
    This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssman antigen.
  • アプリケーション
    適用あり: IHC-P, Agglutinationmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Mixture of erythrocytes of blood group A1 and glycoprotein fraction isolated from the saliva of secretors with blood group A.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: Tissue Culture Supernatant
  • 精製度
    Tissue culture supernatant
  • 特記事項(精製)
    Concentrated by ultrafiltration (100 kDa cut-off). Actual immunoglobulin concentration not determined.
  • ポリ/モノ
    モノクローナル
  • クローン名
    HE-193
  • ミエローマ
    unknown
  • アイソタイプ
    IgM
  • 軽鎖の種類
    unknown
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab2521 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
Agglutination Use at an assay dependent dilution.

ターゲット情報

  • 関連性
    Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
  • 細胞内局在
    Cell Membrane
  • 参照データベース

プロトコール

Anti-Blood Group A Antigen antibody [HE-193] (ab2521) 使用論文

This product has been referenced in:
  • Nemec M  et al. Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine. Vox Sang 52:125-8 (1987). Read more (PubMed: 2440181) »

See 1 Publication for this product

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I have received the following information:

ab2521: the IHC(P) application was tested on human colon carcinoma tissue. The paraffin-embedded sections were deparaffinized by xylene, hydrated by 100%, 90%,...

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Thank you for your enquiry and your interest in our products. We can offer testing discount for untested species/application and also for images for tested application.   I can confirm that ab24222 has not been tested yet in IHC; whilst ab2521 an...

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Thank you for your enquiry. The format of ab2521 is condensed supernatant with 15 mM sodium azide. No more supplements or buffers are added or necessary. We do not store this antibody in 1/20 volume 1M tris buffer solution, pH 8. I hope this info...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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