製品の概要

  • 製品名Anti-BLK antibody
    BLK 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to BLK
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant fragment: MGLVSSKKPD KEKPIKEKDK GQWSPLKVSA QDKDAPPLPP LVVFNHLTPP PPDEHLDEDK HFVVALYDYT AMNDRDLQML KGEKLQVLKG , corresponding to amino acids 1-90 of Human BLK

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab54866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Modulator of beta-cells function, acting through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose.
    • 組織特異性Expressed in lymphatic organs, pancreatic islets, Leydig cells, striate ducts of salivary glands and hair follicles.
    • 関連疾患Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11) [MIM:613375]. MODY11 is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.
    • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
      Contains 1 protein kinase domain.
      Contains 1 SH2 domain.
      Contains 1 SH3 domain.
    • Information by UniProt
    • 参照データベース
    • 別名
      • B lymphocyte kinase antibody
      • B lymphoid tyrosine kinase antibody
      • Blk antibody
      • BLK nonreceptor tyrosine kinase antibody
      • BLK_HUMAN antibody
      • EC 2.7.10.2 antibody
      • MGC 10442 antibody
      • MGC10442 antibody
      • MODY 11 antibody
      • MODY11 antibody
      • P55 BLK antibody
      • p55-BLK antibody
      • Tyrosine kinase B lymphocyte specific antibody
      • Tyrosine protein kinase antibody
      • Tyrosine-protein kinase BLK antibody
      see all

    Anti-BLK antibody 画像



    • Predicted band size : 58 kDa
      BLK antibody (ab54866) at 1ug/lane + Raw cell lysate at 25ug/lane.

    Anti-BLK antibody (ab54866) 使用論文

    ab54866 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your inquiry and I apologize for the delay in this reply as I was awaiting more information from the lab.   We don't have cross-reactivity data for ab54866. It has not been tested for cross-reactivity to Lck, Fyn, Lyn or any other Src ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"