製品の概要

  • 製品名
    Anti-BLAP75 antibody
    BLAP75 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BLAP75
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 275 and 300 of human BLAP75 (NP_079221.1)

  • ポジティブ･コントロール
    • Human skin basal cell carcinoma tissue.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項（精製）
    ab84387 was affinity purified using an epitope specific to BLAP75 immobilized on solid support.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • ターゲット情報

    • 機能
      Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
    • 配列類似性
      Belongs to the RMI1 family.
    • 細胞内局在
      Nucleus. Forms foci in response to DNA damage.
    • Information by UniProt
    • 参照データベース
      • 別名
        • BLAP75 antibody
        • BLM associated polypeptide 75 kDa antibody
        • BLM associated protein 75 kDa antibody
        • BLM-associated protein of 75 kDa antibody
        • C9orf76 antibody
        • FAAP75 antibody
        • FLJ12888 antibody
        • Homolog of yeast RecQ mediated genome instability 1 antibody
        • RecQ mediated genome instability 1 antibody
        • RecQ-mediated genome instability protein 1 antibody
        • Rmi1 antibody
        • RMI1 homolog antibody
        • RMI1 RecQ mediated genome instability 1 homolog antibody
        • RMI1_HUMAN antibody
        • RP11-346I8 antibody
        see all

      画像

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BLAP75 antibody (ab84387)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BLAP75 antibody (ab84387)
        ab84387, at 1/250 dilution, staining BLAP75 in formalin fixed, paraffin embedded human skin basal cell carcinoma tissue by Immunohistochemistry.
        Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1/100.

      プロトコール

      参考文献

      ab84387 has not yet been referenced specifically in any publications.

      ab84387 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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