製品の概要

  • 製品名Anti-Bim antibody
    Bim 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Bim
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide (Human)

  • ポジティブ・コントロール
    • Extracts from COS7 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).

ターゲット情報

  • 機能Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
  • 組織特異性Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.
  • 配列類似性Belongs to the Bcl-2 family.
  • ドメインThe BH3 motif is required for Bcl-2 binding and cytotoxicity.
  • 細胞内局在Mitochondrion and Endomembrane system. Associated with intracytoplasmic membranes.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BCL2 like 11 antibody
    • B2L11_HUMAN antibody
    • BAM antibody
    • Bcl 2 interacting protein Bim antibody
    • Bcl 2 related ovarian death agonist antibody
    • Bcl-2-like protein 11 antibody
    • BCL2 interacting mediator of cell death antibody
    • BCL2 like 11 (apoptosis facilitator) antibody
    • BCL2 like protein 11 antibody
    • Bcl2-interacting mediator of cell death antibody
    • Bcl2-L-11 antibody
    • Bcl2l11 antibody
    • BIM alpha6 antibody
    • BIM antibody
    • BIM beta6 antibody
    • BIM beta7 antibody
    • BimEL antibody
    • BimL antibody
    • BOD antibody
    see all

Anti-Bim antibody 画像

  • All lanes : Anti-Bim antibody (ab53155) at 1/500 dilution

    Lane 1 : extracts from COS7 cells, untreated.
    Lane 2 : extracts from COS7 cells, treated with the immunizing peptide.


    Predicted band size : 22 kDa
    Observed band size : 22 kDa

Anti-Bim antibody (ab53155) 使用論文

ab53155 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab53155.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"