Anti-Bile Acid Receptor NR1H4 抗体 (ab58559)

製品の概要

  • 製品名Anti-Bile Acid Receptor NR1H4 antibody
    Bile Acid Receptor NR1H4 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Bile Acid Receptor NR1H4
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Rabbit, Human
    交差が予測される動物種: Mouse, Cow, Syrian Hamster
  • 免疫原

    Synthetic peptide:

    KSCREKTELTPDQQ

    , corresponding to internal sequence amino acids 251-264 of Human Bile Acid Receptor NR1H4, (NP_005114.1.).

  • ポジティブ・コントロール
    • Human Lung and Duodenal lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab58559 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

    Peptide ELISA: antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
    • 配列類似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BAR antibody
      • Bile acid receptor antibody
      • Farnesoid X activated receptor antibody
      • Farnesoid X receptor antibody
      • Farnesoid X-activated receptor antibody
      • Farnesol receptor HRR 1 antibody
      • Farnesol receptor HRR-1 antibody
      • Farnesol receptor HRR1 antibody
      • FXR antibody
      • HRR 1 antibody
      • HRR1 antibody
      • NR1H4 antibody
      • NR1H4_HUMAN antibody
      • Nuclear receptor subfamily 1 group H member 4 antibody
      • Retinoid X receptor interacting protein 14 antibody
      • Retinoid X receptor-interacting protein 14 antibody
      • RIP 14 antibody
      • RIP14 antibody
      • RXR interacting protein 14 antibody
      • RXR-interacting protein 14 antibody
      see all

    Anti-Bile Acid Receptor NR1H4 antibody 画像

    • Anti-Bile Acid Receptor NR1H4 antibody (ab58559) at 1 µg/ml + Human Lung lysate (35ug protein in RIPA buffer).

      Predicted band size : 56 kDa
      Observed band size : 56 kDa

    Anti-Bile Acid Receptor NR1H4 antibody (ab58559) 使用論文

    ab58559 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Western blot
    Loading amount 50 µg
    Gel Running Conditions Reduced Denaturing (7.5%)
    Sample Rabbit Tissue lysate - whole (liver)
    Specification liver
    Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 7.5% · Temperature: 22°C
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    投稿 Jun 25 2013

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"