製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to BICD2
  • 特異性
    this antibody does not cross react with BICD1.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to a 13 amino acid peptide from near the carboxy terminus of human BICD2.

  • ポジティブ・コントロール
    • A549 cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab73286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa).

ターゲット情報

  • 機能
    May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Belongs to the BicD family.
  • ドメイン
    The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2.
  • 翻訳後修飾
    Phosphorylated by NEK9 in vitro.
  • 細胞内局在
    Golgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bA526D8.1 antibody
    • Bic D 2 antibody
    • Bic-D 2 antibody
    • Bicaudal D homolog 2 (Drosophila) antibody
    • Bicaudal D homolog 2 antibody
    • Bicd2 antibody
    • BICD2_HUMAN antibody
    • Coiled coil protein BICD2 antibody
    • Cytoskeleton like bicaudal D protein homolog 2 antibody
    • Homolog of Drosophila bicaudal D antibody
    • KIAA0699 antibody
    • Protein bicaudal D homolog 2 antibody
    see all

画像

  • Lane 1 : Anti-BICD2 antibody (ab73286) at 1 µg/ml
    Lane 2 : Anti-BICD2 antibody (ab73286) at 2 µg/ml

    Lane 1 : A549 cell lysate
    Lane 2 : A549 cell lysate

    Lysates/proteins at 15 µg/ml per lane.


    Predicted band size : 93 kDa
    Observed band size : 93 kDa

プロトコール

参考文献

This product has been referenced in:
  • Turgay Y  et al. SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol 204:1099-109 (2014). Read more (PubMed: 24662567) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab73286.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録