Anti-BICD2 抗体 (ab73286)
Key features and details
- Rabbit polyclonal to BICD2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-BICD2 antibody
BICD2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to BICD2 -
由来種
Rabbit -
特異性
this antibody does not cross react with BICD1. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to a 13 amino acid peptide from near the carboxy terminus of human BICD2.
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ポジティブ・コントロール
- A549 cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab73286の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa).
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa). |
ターゲット情報
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機能
May play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. -
組織特異性
Ubiquitous. -
配列類似性
Belongs to the BicD family. -
ドメイン
The fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2. -
翻訳後修飾
Phosphorylated by NEK9 in vitro. -
細胞内局在
Golgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology. - Information by UniProt
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参照データベース
- Entrez Gene: 23299 Human
- Omim: 609797 Human
- SwissProt: Q8TD16 Human
- Unigene: 436939 Human
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別名
- bA526D8.1 antibody
- Bic D 2 antibody
- Bic-D 2 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab73286 は 1 報の論文で使用されています。
- Turgay Y et al. SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol 204:1099-109 (2014). PubMed: 24662567